Evidence map›Paper›PMID 33628202›Full record

ArticleFrontiers in immunology2020

Rituximab Induces Complete Remission of Proteinuria in a Patient With Minimal Change Disease and No Detectable B Cells.

Maximilian Webendörfer, Linda Reinhard, Rolf A K Stahl, Thorsten Wiech, Hans-Willi Mittrücker, Sigrid Harendza, Elion Hoxha

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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  7. Review
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  9. Use of rituximab in glomerulopathies.Jornal brasileiro de nefrologia
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Maximilian WebendörferIII. Department of Internal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Linda ReinhardIII. Department of Internal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Rolf A K StahlIII. Department of Internal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Thorsten WiechInstitute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Hans-Willi MittrückerInstitute of Immunology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Sigrid HarendzaIII. Department of Internal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Elion HoxhaIII. Department of Internal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
University Medical Center Hamburg-Eppendorf · DEUniversität Hamburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Minimal change disease (MCD) is a common cause of nephrotic syndrome. Treatment with steroids is usually effective, but frequent relapses are therapeutic challenges. The anti-CD20 antibody rituximab has shown promising results for treatment of steroid-sensitive nephrotic syndrome. Since predictive biomarkers for treatment efficacy and the accurate rituximab dosage for effective induction of remission are unknown, measurement of CD19

Indexed as

AgedB-LymphocytesHumansImmunologic FactorsMaleNephrosis, LipoidProteinuriaRemission InductionRituximabT-LymphocytesImmunologic FactorsRituximabB cell depletion therapyCD20+ T cellsminimal change diseasenephrotic syndromerituximab

Identifiers

PMID33628202
PMCPMC7897659
OpenAlexW3127996958

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.