Evidence map›Paper›PMID 33628062›Full record

ArticleInternational medical case reports journal2021

Iron Deficiency Anemia Refractory to Conventional Therapy but Responsive to Feralgine

Valentina Talarico, Laura Giancotti, Roberto Miniero, Marco Bertini

Open access · goldAbstract readCase Reports
In one paragraph

Article in International medical case reports journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Valentina TalaricoDepartment of Pediatric, Pugliese-Ciaccio Hospital, Catanzaro, Italy.ORCID 0000-0001-9027-6921
Laura GiancottiUnit of Pediatrics, University "Magna Graecia", Catanzaro, Italy.
Roberto MinieroDepartment of Pediatric, Pugliese-Ciaccio Hospital, Catanzaro, Italy.ORCID 0000-0002-5716-4730
Marco BertiniR&D Department, Laboratori Baldacci SpA, Pisa, Italy.ORCID 0000-0003-1469-7825
Azienda Ospedaliera Pugliese Ciaccio · ITBaldacci (Italy) · ITMagna Graecia University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Iron, which is an important micronutrient in the human body may be deficient in people with celiac disease (CD). Iron deficiency anemia (IDA) may be the presenting feature of celiac disease, also in the absence of diarrhea or weight loss. The treatment of IDA in patient with CD is primarily a gluten-free-diet (GFD), but it is also very important oral iron supplementation until the iron stores have been restored. However, a frequent problem in CD is the poor tolerability and poor efficacy of oral iron preparations. A new product, consisting of the combination of Ferrous Bysglicinate Chelate and Sodium Alginate (Feralgine™), has been demonstrated to be more bioavailable and well tolerated in CD. We present a case report that showed a clear efficacy of this product in a form of IDA refractory to conventional therapy in a woman with CD and we demonstrated a clear increase of serum iron after administration of this new type of ferrous.

Indexed as

celiac diseaseferrous bisglycinate chelateiron deficiency anemiaOIATsodium alginate

Identifiers

PMID33628062
PMCPMC7897862
OpenAlexW3130004856

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.