Evidence map›Paper›PMID 33628016›Full record

ArticleClinical interventions in aging2021

Mirabegron Alleviates the Degree of Burden Experienced by Caregivers of Older Females with Mixed or Urge Incontinence: A Prospective Study.

Athanasios Zachariou, Maria Filiponi, Aris Kaltsas, Fotios Dimitriadis, Ioannis Champilomatis, Athanasios Paliouras, Panagiota Tsounapi, Charalampos Mamoulakis, Atsushi Takenaka, Nikolaos Sofikitis

Open access · goldAbstract read
In one paragraph

Article in Clinical interventions in aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Athanasios ZachariouUrology Department, School of Medicine, Ioannina University, Ioannina, Greece.
Maria FiliponiIncontinence Unit, Physical Medicine and Rehabilitation Centre EU PRATTEIN, Volos, Greece.
Aris KaltsasUrology Department, School of Medicine, Ioannina University, Ioannina, Greece.ORCID 0000-0003-4651-312X
Fotios Dimitriadis1 Urology Department, School of Medicine, Aristotle University, Thessaloniki, Greece.ORCID 0000-0003-1198-9144
Ioannis ChampilomatisUrology Department, School of Medicine, Ioannina University, Ioannina, Greece.
Athanasios PaliourasUrology Department, School of Medicine, Ioannina University, Ioannina, Greece.
Panagiota TsounapiUrology Department, School of Medicine, Tottori University, Yonago, Japan.
Charalampos MamoulakisUrology Department, Medical School, University of Crete, Heraklion, Greece.ORCID 0000-0002-8662-1275
Atsushi TakenakaUrology Department, School of Medicine, Tottori University, Yonago, Japan.
Nikolaos SofikitisUrology Department, School of Medicine, Ioannina University, Ioannina, Greece.
University of Ioannina · GRTottori University · JPAristotle University of Thessaloniki · GRMaterials Industrial Research and Technology Development Centre (Greece) · GRUniversity of Crete · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeOlder people, especially women, have the highest known prevalence of urinary incontinence (UI) of any other age-group. Continual care provision for elderly incontinent females is an incredibly arduous process, yet only very few studies have investigated the issue. Aim of the study was to evaluate the impact of mirabegron's treatment on the degree of burden experienced by caregivers of elderly female patients with UI. PATIENTS AND

methodsA hundred and eighty-six caregivers of older females with mixed or urgency UI besides various conditions (strokes, post-operative recovery after major surgery, etc.) were included in the study. Group A comprised 91 patients that did not want to receive any treatment for UI. Group B consisted of 95 elderly females treated for UI with mirabegron 50 mg/daily for three months. All caregivers completed the Zarit Burden Scale (ZBS) questionnaire at the outset and after the three months. All patients completed a bladder diary at the beginning and at the end of the observation/medication period.

resultsPatients receiving mirabegron presented a statistically significant improvement in UI parameters. Their caregivers showed a statistically significant decrease in the ZBS total score as well as separate domains.

conclusionThis pilot study confirms that mirabegron administration can improve the quality of life of older females suffering from UI while substantially relieving caregiver burden. Recognizing the physical and emotional reactions of caregivers may help health providers deliver better support and resources to meet the needs of caregivers and patients alike.

Indexed as

Caregiver BurdenQuality of LifeUrinary IncontinenceAcetanilidesAgedCaregiversFemaleHumansOutcome Assessment, Health CarePilot ProjectsSurveys and QuestionnairesThiazolesUrological AgentsAcetanilidesmirabegronThiazolesUrological AgentsagingcaregiverincontinencemirabegronZarit Burden Scale

Identifiers

PMID33628016
PMCPMC7897712
OpenAlexW3130174281

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.