ArticleNature2021
A mechanosensitive peri-arteriolar niche for osteogenesis and lymphopoiesis.
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Article in Nature, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 186 papers.
0numbers the graph read from it
0cells of the map it votes in
186citing papers in PubMed
25.5field-weighted citation impact, top 1% of its field
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
186 citing papers in PubMed, 277 citations in OpenAlex.
- Piezo1-mediated mechanotransduction in bone formation and fracture repair.Biochemistry and biophysics reports · 2026Review
- Endothelial PERK restricts lymphoid regeneration by reducing DLL4-NOTCH3 signaling at the Pre-B niche.Cell reports · 2026Article
- Skeletal stem and progenitor cell niche organization, regulation and repair.Reviews in endocrine & metabolic disorders · 2026Review
- Stem cells as an essential mediator of the exercise-tumorigenesis link.Nature reviews. Cancer · 2026Review
- Targeting AMPK signaling in nucleus pulposus cells ameliorates spaceflight microgravity-induced intervertebral disc degeneration.Cell death and differentiation · 2026Article
- Transcriptomic insights into exercise-induced trabecular bone microarchitectural adaptations following combined aerobic and resistance training in mice.Scientific reports · 2026Article
- Sulfated polysaccharide prevents senescent adipocyte-driven osteonecrosis by stem cell fate reprogramming.Bioactive materials · 2026Article
- Epigenetic programming by H3K23ac defines lineage fate of Meg3Nature cell biology · 2026Article
- Aging mechanisms and rejuvenation strategies for hematopoietic stem cells.Genome biology · 2026Review
- Targeting coupling of type H-like vessels and cell fate transition to delay soft tissue aging.Nature communications · 2026Article
- Longitudinal localization of leukaemic stem cells between the metaphysis and central marrow governs their behaviour.Nature cell biology · 2026Article
- Identification of a new population of TnnBone research · 2026Article
- Single-cell technologies drive mechanistic insights and therapeutic translation in skeletal system research.iScience · 2026Review
- Article
- Ultrasound-Generated Nanoscale Mechanical Stimulation to Regulate Stem Cell Differentiation.ACS nanoscience Au · 2026Article
- Bone matrix proteins: regulators of skeletal remodeling and repair.Journal of bone and mineral metabolism · 2026Review
- The bone marrow microenvironment during homeostasis and after myeloablation.Journal of bone and mineral metabolism · 2026Review
- Bridging skeletal stem cell diversity and human skeletal modeling.Journal of bone and mineral metabolism · 2026Review
- Accelerometer-measured weekly and diurnal moderate-to-vigorous physical activity patterns and incident osteoporosis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026Article
- Piezo1-dependent activation of stromal cells ignites muscle inflammation in exercise and injury and is associated with inflammaging.Nature immunology · 2026Article
126 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
23 authors at 5 institutions in 2 countries.
Bo ShenChildren's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID http://orcid.org/0000-0002-5237-6144
Alpaslan TasdoganChildren's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID http://orcid.org/0000-0003-2543-852X
Jessalyn M UbellackerChildren's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Jingzhu ZhangChildren's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Elena D NosyrevaDepartment of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Liming DuChildren's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Malea M MurphyChildren's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID http://orcid.org/0000-0001-7071-6862
Shuiqing HuDepartment of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Yating YiDepartment of Restorative Sciences, School of Dentistry, Texas A&M University, Dallas, TX, USA.
Nergis KaraChildren's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Xin LiuChildren's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Shay GuelaChildren's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Yuemeng JiaChildren's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Vijayashree RameshChildren's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Claire EmbreeChildren's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Evann C MitchellChildren's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Yunduo C ZhaoSchool of Biomedical Engineering, Heart Research Institute and Charles Perkins Center, The University of Sydney, Darlington, New South Wales, Australia.ORCID http://orcid.org/0000-0002-1802-2318
Lining A JuSchool of Biomedical Engineering, Heart Research Institute and Charles Perkins Center, The University of Sydney, Darlington, New South Wales, Australia.ORCID http://orcid.org/0000-0002-7591-0864
Zhao HuSchool of Biomedical Engineering, Heart Research Institute and Charles Perkins Center, The University of Sydney, Darlington, New South Wales, Australia.
Genevieve M CraneRobert J. Tomsich Pathology & Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OH, USA.
Zhiyu ZhaoChildren's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID http://orcid.org/0000-0001-6308-6997
Ruhma SyedaDepartment of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Sean J MorrisonChildren's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA. Sean.Morrison@UTSouthwestern.edu.ORCID http://orcid.org/0000-0003-1587-8329
The University of Texas Southwestern Medical Center · USThe University of Sydney · AUCleveland Clinic · USHoward Hughes Medical Institute · USTexas A&M University · US
Funding
The Metabolic Regulation of Hematopoietic Stem Cell FunctionR01DK118745 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI MORRISON, SEAN J · 2019 to 2023
$1.8MCharacterization of a new growth factor from a bone marrow vascular nicheF32HL139016 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI SHEN, BO · 2017 to 2019
$179kAmerican Heart Association-American Stroke AssociationHoward Hughes Medical InstituteNHLBI NIH HHS F32 HL139016NIDDK NIH HHS R01 DK118745
Abstract
Stromal cells in adult bone marrow that express leptin receptor (LEPR) are a critical source of growth factors, including stem cell factor (SCF), for the maintenance of haematopoietic stem cells and early restricted progenitors
Indexed as
ArteriolesLymphopoiesisOsteogenesisStem Cell NicheAdipose TissueAgingAnimalsBone and BonesBone Marrow CellsFemaleHematopoietic Cell Growth FactorsLectins, C-TypeLymphocytesMaleMiceReceptors, LeptinClec11A protein, mouseHematopoietic Cell Growth FactorsLectins, C-Typeleptin receptor, mouseReceptors, LeptinStem Cell Factor
Identifiers
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.