Evidence map›Paper›PMID 33627827›Full record

ArticleGenetics in medicine : official journal of the American College of Medical Genetics2021

Expanding evidence leads to new pharmacogenomics payer coverage.

Philip E Empey, Victoria M Pratt, James M Hoffman, Kelly E Caudle, Teri E Klein

Abstract read
In one paragraph

Article in Genetics in medicine : official journal of the American College of Medical Genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. A systematic review of real-world evidence on the clinical relevance, characterization, and utility ofJournal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques · 2025
    Pooled it
  2. Pooled it
  3. Article
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  7. Article
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  9. Pharmacogenetics: Opportunities for theAnnual review of pharmacology and toxicology · 2025
    Review
  10. Article
  11. Circulation · 2024
    Review
  12. Strategies for DPYD testing prior to fluoropyrimidine chemotherapy in the US.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
  13. Review
  14. Article
  15. Article
  16. Pharmacogenetics of Antiplatelet Therapy.Annual review of pharmacology and toxicology · 2023
    Review
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  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Philip E EmpeyDepartment of Pharmacy and Therapeutics, University of Pittsburgh, Pittsburgh, PA, USA. pempey@pitt.edu.ORCID http://orcid.org/0000-0001-7474-2339
Victoria M PrattDepartment of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA.
James M HoffmanOffice of Quality & Patient Care, St. Jude Children's Research Hospital, Memphis, TN, USA.
Kelly E CaudleDepartment of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.
Teri E KleinDepartment of Biomedical Data Science and Medicine, Stanford University, Stanford, CA, USA.

Funding

PharmGKB: pharmacogenomics discovery and implementationU24HG010615 · NHGRI · STANFORD UNIVERSITY · PI TERI Ellen KLEIN, Michelle Whirl-Carrillo · 2020 to 2026
$9.5M
Implementing genomic medicine through pragmatic trials in diverse and underserved populations across Indiana.U01HG010245 · NHGRI · INDIANA UNIVERSITY INDIANAPOLIS · PI DEXTER, PAUL, SKAAR, TODD C. · 2018 to 2024
$9.4M
Clinical Pharmacogenetics Implementation Consortium (CPIC)U24HG010135 · NHGRI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI CAUDLE, KELLY E., KLEIN, TERI ELLEN · 2018 to 2022
$5.4M
Embedding Pharmacogenotyping in an Integrated Health System for the UnderservedU01HG007762 · NHGRI · INDIANA UNIVERSITY INDIANAPOLIS · PI DEXTER, PAUL, SKAAR, TODD C. · 2014 to 2018
$4.4M
Pharmacogenomics Clinical Annotation Tool (PharmCAT)U24HG010862 · NHGRI · UNIVERSITY OF PENNSYLVANIA · PI KLEIN, TERI ELLEN, RITCHIE, MARYLYN D · 2020 to 2022
$1.7M
NHGRI NIH HHS U01 HG007762NHGRI NIH HHS U01 HG010245NHGRI NIH HHS U24 HG010135NHGRI NIH HHS U24 HG010615NHGRI NIH HHS U24 HG010862
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

PharmacogeneticsHumans

Identifiers

PMID33627827
PMCPMC8222707

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.