Evidence map›Paper›PMID 33627808›Full record

ArticleNature2021

Spatiotemporal dissection of the cell cycle with single-cell proteogenomics.

Diana Mahdessian, Anthony J Cesnik, Christian Gnann, Frida Danielsson, Lovisa Stenström, Muhammad Arif, Cheng Zhang, Trang Le, Fredric Johansson, Rutger Schutten and 14 more

Erratum issuedAbstract read
PubMed Publisher
In one paragraph

Article in Nature, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 132 papers.

0numbers the graph read from it
0cells of the map it votes in
132citing papers in PubMed
18.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

132 citing papers in PubMed, 208 citations in OpenAlex.

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  19. Cell cycle in plant development and reprogramming.Development (Cambridge, England) · 2026
    Review
  20. Article

72 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

24 authors at 4 institutions in 3 countries.

Diana Mahdessian *Science for Life Laboratory, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH - Royal Institute of Technology, Stockholm, Sweden.
Anthony J Cesnik *Science for Life Laboratory, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH - Royal Institute of Technology, Stockholm, Sweden.ORCID http://orcid.org/0000-0002-5326-7134
Christian GnannScience for Life Laboratory, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH - Royal Institute of Technology, Stockholm, Sweden.
Frida DanielssonScience for Life Laboratory, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH - Royal Institute of Technology, Stockholm, Sweden.
Lovisa StenströmScience for Life Laboratory, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH - Royal Institute of Technology, Stockholm, Sweden.
Muhammad ArifScience for Life Laboratory, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH - Royal Institute of Technology, Stockholm, Sweden.ORCID http://orcid.org/0000-0003-2261-0881
Cheng ZhangScience for Life Laboratory, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH - Royal Institute of Technology, Stockholm, Sweden.ORCID http://orcid.org/0000-0002-3721-8586
Trang LeScience for Life Laboratory, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH - Royal Institute of Technology, Stockholm, Sweden.
Fredric JohanssonScience for Life Laboratory, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH - Royal Institute of Technology, Stockholm, Sweden.ORCID http://orcid.org/0000-0001-5160-9543
Rutger SchuttenScience for Life Laboratory, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH - Royal Institute of Technology, Stockholm, Sweden.
Anna BäckströmScience for Life Laboratory, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH - Royal Institute of Technology, Stockholm, Sweden.
Ulrika AxelssonScience for Life Laboratory, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH - Royal Institute of Technology, Stockholm, Sweden.
Peter ThulScience for Life Laboratory, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH - Royal Institute of Technology, Stockholm, Sweden.ORCID http://orcid.org/0000-0002-6107-1465
Nathan H ChoChan Zuckerberg Biohub, San Francisco, San Francisco, CA, USA.
Oana CarjaDepartment of Genetics, Stanford University, Stanford, CA, USA.
Mathias UhlénScience for Life Laboratory, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH - Royal Institute of Technology, Stockholm, Sweden.ORCID http://orcid.org/0000-0002-4858-8056
Adil MardinogluScience for Life Laboratory, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH - Royal Institute of Technology, Stockholm, Sweden.
Charlotte StadlerScience for Life Laboratory, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH - Royal Institute of Technology, Stockholm, Sweden.
Cecilia LindskogDepartment of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.ORCID http://orcid.org/0000-0001-5611-1015
Burcu AyogluScience for Life Laboratory, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH - Royal Institute of Technology, Stockholm, Sweden.ORCID http://orcid.org/0000-0001-7843-2960
Manuel D LeonettiChan Zuckerberg Biohub, San Francisco, San Francisco, CA, USA.
Fredrik PonténDepartment of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.ORCID http://orcid.org/0000-0003-0703-3940
Devin P SullivanScience for Life Laboratory, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH - Royal Institute of Technology, Stockholm, Sweden.
Emma LundbergScience for Life Laboratory, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH - Royal Institute of Technology, Stockholm, Sweden. emma.lundberg@scilifelab.se.ORCID http://orcid.org/0000-0001-7034-0850
Science for Life Laboratory · SEChan Zuckerberg Initiative (United States) · USUppsala University · SEKing's College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cell cycle, over which cells grow and divide, is a fundamental process of life. Its dysregulation has devastating consequences, including cancer

Indexed as

Cell CycleTranscriptomeCell Cycle ProteinsCell LineageCell Line, TumorCell ProliferationHumansInterphaseMitosisOncogene ProteinsPhosphorylationProtein KinasesProteogenomicsProteomeSingle-Cell AnalysisTime FactorsCell Cycle ProteinsOncogene ProteinsProtein KinasesProteome

Identifiers

PMID33627808
OpenAlexW3132829024

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.