Evidence map›Paper›PMID 33627768›Full record

ArticleScientific reports2021

Intraoperative ureter identification with a novel fluorescent catheter.

Manuel Barberio, Mahdi Al-Taher, Eric Felli, Anila Hoskere Ashoka, Jacques Marescaux, Andrey Klymchenko, Michele Diana

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

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  8. Clinically Translatable Solid-State Dye for NIR-II Imaging of Medical Devices.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
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  11. BFMolecules (Basel, Switzerland) · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Manuel BarberioInstitute of Image-Guided Surgery, IHU-Strasbourg, 1, place de l'Hôpital, 67091, Strasbourg, France. manuel.barberio@ihu-strasbourg.eu.
Mahdi Al-TaherResearch Institute Against Digestive Cancer, IRCAD, Strasbourg, France.
Eric FelliInstitute of Image-Guided Surgery, IHU-Strasbourg, 1, place de l'Hôpital, 67091, Strasbourg, France.
Anila Hoskere AshokaLaboratoire de Bio-Imagerie et Pathologies, UMR 7021, CNRS, Université de Strasbourg, Strasbourg, France.
Jacques MarescauxResearch Institute Against Digestive Cancer, IRCAD, Strasbourg, France.
Andrey KlymchenkoLaboratoire de Bio-Imagerie et Pathologies, UMR 7021, CNRS, Université de Strasbourg, Strasbourg, France.
Michele DianaResearch Institute Against Digestive Cancer, IRCAD, Strasbourg, France.
Institut de Recherche contre les Cancers de l’Appareil Digestif · FRCentre National de la Recherche Scientifique · FRInstitut de Chirurgie Guidée par l'Image · FRUniversité de Strasbourg · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Iatrogenic ureteral injuries (IUI) occur in 0.5-1.3% of cases during abdominal surgery. If not recognized intraoperatively, IUI increase morbidity/mortality. A universally accepted method to prevent IUI is lacking. Near-infrared fluorescent imaging (NIRF), penetrating deeper than normal light within the tissue, might be useful, therefore ureter visualization combining NIRF with special dyes (i.e. IRDye 800BK) is promising. Aim of this work is to evaluate the detection of ureters using stents coated with a novel biocompatible fluorescent material (NICE: near-infrared coating of equipment), during laparoscopy. female pigs underwent placement of NICE-coated stents (NS). NIRF was performed, and fluorescence intensity (FI) was computed. Successively, 0.15 mg/kg of IRDye 800BK was administered intravenously, and FI was computed at different timepoints. Ureter visualization using NS only was further assessed in a human cadaver. Both methods allowed in vivo ureter visualization, with equal FI. However, NS were constantly visible whereas IRDye 800BK allowed visualization exclusively during the ureteral peristaltic phases. In the human cadaver, NS provided excellent ureter visualization in its natural anatomical position. NS provided continuous ureteral visualization with similar FI as the IRDye 800BK, which exclusively allowed intermittent visualization, dependent on ureteral peristalsis. NS might prove useful to visualize ureters intraoperatively, potentially preventing IUI.

Indexed as

CadaverCathetersFluorescenceFluorescent DyesHumansLaparoscopyOptical ImagingUreterFluorescent Dyes

Identifiers

PMID33627768
PMCPMC7904916
OpenAlexW3133418987

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.