ArticleScientific reports2021
Three-dimensional tonotopic mapping of the human cochlea based on synchrotron radiation phase-contrast imaging.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 3 of them syntheses that pooled it.
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Who cites it
50 citing papers in PubMed, 3 syntheses or guidelines pooled it, 109 citations in OpenAlex.
- Pooled it
- Pooled it
- Suitable Electrode Choice for Robotic-Assisted Cochlear Implant Surgery: A Systematic Literature Review of Manual Electrode Insertion Adverse Events.Frontiers in surgery · 2022Pooled it
- Structural and Molecular Evidence for a Frequency-Dependent Electrochemical Gradient in the Human Cochlear Lateral Wall.Journal of the Association for Research in Otolaryngology : JARO · 2026Article
- Micro-CT Evaluation of Robot-Assisted Insertion of CI632 Implant in Human Cadaveric Temporal Bones.The Laryngoscope · 2026Article
- The Retrotympanum Revisited By a Volumetric Approach Using Synchrotron-Based X-Ray Phase-Contrast Imaging.Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2026Article
- The cochlear morphometry compendium: High-resolution synchrotron measurements and normative reference values.Journal of anatomy · 2026Article
- Cochlear Implant Insertion Trauma Is Associated With Spiral Ganglion Neuron "Dead Zones" in the Human.Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2026Article
- Cochlear Implantation and Facial Nerve Stimulation: Clinical and Anatomic Correlations.The Laryngoscope · 2026Article
- High resolution, contrast-enhanced X-ray microscopy of theFrontiers in neuroscience · 2026Article
- Review
- The cochlear apex demystified: Implications from synchrotron radiation phase-contrast imaging and microscopy for cochlear implantation.Journal of anatomy · 2025Article
- Synchrotron-Based Trauma Assessment of Robotic Electrode Insertions in Cochlear Implantation.The Laryngoscope · 2025Article
- Chronic Auditory-Nerve Implant Enhances Brainstem Phase Locking to Electric Pulse Trains.Journal of the Association for Research in Otolaryngology : JARO · 2025Article
- Spiner, deep learning-based automated detection of spiral ganglion neurons in intact cochleae.iScience · 2025Article
- The State of High-Resolution Imaging of the Human Inner Ear: A Look Into the Black Box.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Article
- 3D virtual histology of rodent and primate cochleae with multi-scale phase-contrast X-ray tomography.Scientific reports · 2025Article
- Learning to hear again with alternating cochlear frequency allocations.Scientific reports · 2025Article
- The Greenwood function shows close alignment with pitch perceived by cochlear implant patients with long, flexible electrode arrays and fine-structure stimulation.Frontiers in neuroscience · 2025Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The human cochlea transforms sound waves into electrical signals in the acoustic nerve fibers with high acuity. This transformation occurs via vibrating anisotropic membranes (basilar and tectorial membranes) and frequency-specific hair cell receptors. Frequency-positions can be mapped within the cochlea to create a tonotopic chart which fits an almost-exponential function with lowest frequencies positioned apically and highest frequencies positioned at the cochlear base (Bekesy 1960, Greenwood 1961). To date, models of frequency positions have been based on a two-dimensional analysis with inaccurate representations of the cochlear hook region. In the present study, the first three-dimensional frequency analysis of the cochlea using dendritic mapping to obtain accurate tonotopic maps of the human basilar membrane/organ of Corti and the spiral ganglion was performed. A novel imaging technique, synchrotron radiation phase-contrast imaging, was used and a spiral ganglion frequency function was estimated by nonlinear least squares fitting a Greenwood-like function (F = A (10
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