Evidence map›Paper›PMID 33627686›Full record

ArticleScientific reports2021

Combination of a T cell activating therapy and anti-phosphatidylserine enhances anti-tumour immune responses in a HPV16 E7-expressing C3 tumour model.

Brennan S Dirk, Genevieve Weir, Tara Quinton, Olga Hrytsenko, Marianne M Stanford

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Brennan S DirkIMV Inc, Dartmouth, NS, Canada.
Genevieve WeirIMV Inc, Dartmouth, NS, Canada.
Tara QuintonIMV Inc, Dartmouth, NS, Canada.
Olga HrytsenkoIMV Inc, Dartmouth, NS, Canada.
Marianne M StanfordIMV Inc, Dartmouth, NS, Canada. mstanford@imv-inc.com.

Funding

VLP VACCINES AGAINST HPV INDUCED TUMORSR01CA074397 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI KAST, WIJBE MARTIN · 1997 to 2020
$5.5M
NCI NIH HHS R01 CA074397
6 · The paper itself

Abstract

DPX is a novel delivery platform that generates targeted CD8

Indexed as

AnimalsCD8-Positive T-LymphocytesCell Line, TumorDisease Models, AnimalFemaleImmunityImmunotherapyMiceMice, Inbred C57BLPapillomavirus E7 ProteinsPhosphatidylserinesProgrammed Cell Death 1 ReceptorT-Lymphocytes, CytotoxicTumor Microenvironmentoncogene protein E7, Human papillomavirus type 16Papillomavirus E7 ProteinsPhosphatidylserinesProgrammed Cell Death 1 Receptor

Identifiers

PMID33627686
PMCPMC7904807

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.