ArticleNature communications2021
SIV-induced terminally differentiated adaptive NK cells in lymph nodes associated with enhanced MHC-E restricted activity.
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Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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30citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
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Who cites it
30 citing papers in PubMed, 42 citations in OpenAlex.
- Constitutive natural killer cell features associated with post-treatment control of SIV infection in the pVISCONTI study.Nature communications · 2026Article
- Long-term depletion of KIR3DL01+ NK cells by adeno-associated viral-vectored antibody delivery alters chronic SIV infection.PLoS pathogens · 2026Article
- Resident CD49aScience advances · 2026Article
- Harnessing innate immunity: natural killer cells and innate immune responses in reservoir clearance.Current opinion in HIV and AIDS · 2025Review
- NKp30 and NKG2D contribute to natural killer cell-mediated recognition of HIV-infected cells.iScience · 2025Article
- Viremic non-progression in HIV/SIV infection: A tied game between virus and host.Cell reports. Medicine · 2025Review
- Combining a rhesus cytomegalovirus/SIV vaccine with a neutralizing antibody to protect against SIV challenges in rhesus macaques.Frontiers in microbiology · 2025Article
- Post-translational modification of NK cell receptors offers clues to antigenic specificity riddle.Frontiers in immunology · 2025Review
- SARS-CoV-2 viral persistence in lung alveolar macrophages is controlled by IFN-γ and NK cells.Genes and immunity · 2024Article
- Genetic barrier to resistance: a critical parameter for efficacy of neutralizing monoclonal antibodies against SARS-CoV-2 in a nonhuman primate model.Journal of virology · 2024Article
- Antigen-specific memory NK cell responses against HIV and influenza use the NKG2/HLA-E axis.Science immunology · 2023Article
- SARS-CoV-2 viral persistence in lung alveolar macrophages is controlled by IFN-γ and NK cells.Nature immunology · 2023Article
- Multimeric immunotherapeutic complexes activating natural killer cells towards HIV-1 cure.Journal of translational medicine · 2023Article
- T cell activation is insufficient to drive SIV disease progression.JCI insight · 2023Article
- Mapping the interplay between NK cells and HIV: therapeutic implications.Journal of leukocyte biology · 2023Review
- Malaria-driven expansion of adaptive-like functional CD56-negative NK cells correlates with clinical immunity to malaria.Science translational medicine · 2023Article
- NK cell education: Physiological and pathological influences.Frontiers in immunology · 2023Review
- Progress Note 2024: Curing HIV; Not in My Lifetime or Just Around the Corner?Pathogens & immunity · 2023Article
- Limited impact of fingolimod treatment during the initial weeks of ART in SIV-infected rhesus macaques.Nature communications · 2022Article
- NK cell spatial dynamics and IgA responses in gut-associated lymphoid tissues during SIV infections.Communications biology · 2022Article
Corrections and comments
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Authors and funding
21 authors at 7 institutions in 3 countries.
Nicolas HuotInstitut Pasteur, Unité HIV, Inflammation et Persistance, Paris, France.ORCID http://orcid.org/0000-0001-5982-7991
Philippe RascleInstitut Pasteur, Unité HIV, Inflammation et Persistance, Paris, France.
Caroline PetitdemangeInstitut Pasteur, Unité HIV, Inflammation et Persistance, Paris, France.
Vanessa ContrerasCEA-Université Paris Sud-Inserm, U1184, IDMIT Department, IBFJ, Fontenay-aux-Roses, France.
Christina M StürzelUlm University Medical Center, Ulm, Germany.
Eduard BaqueroInstitut Pasteur, Unité de Virologie Structurale, Paris, France.
Justin L HarperDivision of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA.ORCID http://orcid.org/0000-0002-6948-3501
Caroline PassaesInstitut Pasteur, Unité HIV, Inflammation et Persistance, Paris, France.ORCID http://orcid.org/0000-0002-0813-2521
Rachel LegendreBioinformatics and Biostatistics Hub, Department of Computational Biology, Institut Pasteur, Paris, France.ORCID http://orcid.org/0000-0002-5196-9431
Hugo VaretBiomics Platform, Center for Technological Resources and Research (C2RT), Institut Pasteur, Paris, France.ORCID http://orcid.org/0000-0003-3980-4463
Yoann MadecInstitut Pasteur; Epidemiology of Emerging Diseases Unit, Paris, France.ORCID http://orcid.org/0000-0002-6201-1261
Ulrike SauermannDeutsches Primatenzentrum - Leibniz Institut für Primatenforschung, Göttingen, Germany.ORCID http://orcid.org/0000-0001-6229-046X
Christiane Stahl-HennigDeutsches Primatenzentrum - Leibniz Institut für Primatenforschung, Göttingen, Germany.
Jacob NattermannMedizinische Klinik und Poliklinik I, Universitätsklinikum Bonn, Germany; German Center for Infection Research (DZIF), Bonn, Germany.
Asier Saez-CirionInstitut Pasteur, Unité HIV, Inflammation et Persistance, Paris, France.ORCID http://orcid.org/0000-0003-2406-7536
Roger Le GrandCEA-Université Paris Sud-Inserm, U1184, IDMIT Department, IBFJ, Fontenay-aux-Roses, France.
R Keith ReevesCenter for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0003-3157-2557
Mirko PaiardiniDivision of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA.ORCID http://orcid.org/0000-0002-7276-3600
Frank KirchhoffUlm University Medical Center, Ulm, Germany.ORCID http://orcid.org/0000-0002-7052-2360
Beatrice JacquelinInstitut Pasteur, Unité HIV, Inflammation et Persistance, Paris, France.ORCID http://orcid.org/0000-0002-1896-5092
Michaela Müller-TrutwinInstitut Pasteur, Unité HIV, Inflammation et Persistance, Paris, France. mmuller@pasteur.fr.ORCID http://orcid.org/0000-0002-3854-2396
Institut Pasteur · FREmory University · USGerman Primate Center · DEUniversität Ulm · DEUniversité Paris-Sud · FRBeth Israel Deaconess Medical Center · USUniversity Hospital Bonn · DE
Funding
Yerkes National Primate Research Center Role of type-I IFN in regulating COVID-19 induced inflammation and pathogenesisP51OD011132 · OD · EMORY UNIVERSITY · PI Joon Sup Lee · 2012 to 2026
$167.0MViral Testing Core-Maintenance of the SPF Breeding Colonies at Yerkes National Primate Research CenterU42OD011023 · OD · EMORY UNIVERSITY · PI Joyce Kimberly Cohen · 2018 to 2026
$17.5MImmune based interventions for HIV eradicationR01AI116379 · NIAID · EMORY UNIVERSITY · PI PAIARDINI, MIRKO · 2015 to 2019
$4.2MMechanisms of Natural Killer Cell Clearance of SIV from Lymphoid FolliclesR01AI143457 · NIAID · DUKE UNIVERSITY · PI REEVES, ROGER KEITH · 2019 to 2023
$3.1MNIAID NIH HHS R01 AI116379NIAID NIH HHS R01 AI143457NIH HHS P51 OD011132NIH HHS U42 OD011023
Abstract
Natural killer (NK) cells play a critical understudied role during HIV infection in tissues. In a natural host of SIV, the African green monkey (AGM), NK cells mediate a strong control of SIVagm infection in secondary lymphoid tissues. We demonstrate that SIVagm infection induces the expansion of terminally differentiated NKG2a
Indexed as
AlgorithmsAnimalsCD4-Positive T-LymphocytesCell DifferentiationChlorocebus aethiopsFemaleFlow CytometryFluorescent Antibody TechniqueHumansK562 CellsKiller Cells, NaturalLymph NodesLymphoid TissueMacacaMaleNK Cell Lectin-Like Receptor Subfamily CKlrc2 protein, mouseNK Cell Lectin-Like Receptor Subfamily C
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.