ArticleOccupational and environmental medicine2021
First trimester employment, working conditions and preterm birth: a prospective population-based cohort study.
Article in Occupational and environmental medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 18 citations in OpenAlex.
- The effects of prenatal psychosocial work stress on adverse pregnancy outcomes: A comprehensive systematic review and meta-analysis.Scandinavian journal of work, environment & health · 2025Pooled it
- Maternal Occupational Risk Factors and Preterm Birth: A Systematic Review and Meta-Analysis.Public health reviews · 2023Pooled it
- Risk Factors for Working Pregnant Women and Potential Adverse Consequences of Exposure: A Systematic Review.International journal of public health · 2023Pooled it
- Effect of a chimney-fitted improved stove on pregnancy outcomes in Northwest Ethiopia: a randomized controlled trial.BMC pregnancy and childbirth · 2024Trial
- Development of a quantitative job exposure matrix for standing, walking, and forward bending among pregnant workers - The PRECISE JEM.Scandinavian journal of work, environment & health · 2025Article
- Sociodemographic and occupational factors influencing pregnant workers' awareness and utilization of the New York City Pregnant Workers Fairness Act.BMC public health · 2025Article
- Fertility Preservation and Treatment Coverage Among United States Plastic Surgery Trainees.Plastic and reconstructive surgery. Global open · 2025Article
- Women's Health and Working Life: A Scoping Review.International journal of environmental research and public health · 2023Article
- Occupational physical activity as a determinant of daytime activity patterns and pregnancy and infant health.PloS one · 2023Article
- Working conditions in low risk nulliparous women in The Netherlands: are legislation and guidelines a guarantee for a healthy working environment? A cohort study.International archives of occupational and environmental health · 2022Article
- Work-Related Stress, Health Status, and Status of Health Apps Use in Korean Adult Workers.International journal of environmental research and public health · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo explore the association between working conditions during first trimester and total preterm birth (PTB), and subtypes: spontaneous PTB and iatrogenic PTB, additionally to explore the role of hypertension.
methodsPregnant women from the Amsterdam Born Children and their Development study, filled out a questionnaire between January 2003 and March 2004, two weeks after first prenatal screening (singleton liveborn, n=7561). Working conditions were working hours/week, standing/walking hours/week, physical work load and job strain.
resultsProlonged standing/walking during first trimester was associated with an increased risk for total PTB (OR=1.5; 95% CI 1.0-2.3, after adjustments). Other working conditions were not related to total PTB. The separation into spontaneous and iatrogenic PTB revealed that standing/walking was associated with iatrogenic PTB only (OR=2.09; 95% CI 1.00-4.97). The highest risk was found for the combination of a long workweek with high physical work load (OR=3.42; 95% CI 1.04-8.21). Hypertension did not mediate these associations; however, stratified analysis revealed that high physical work load was only related to iatrogenic PTB when pregnancy-induced hypertension was present (OR=6.44; 95% CI 1.21-29.76).
conclusionThis study provides evidence that high physically demanding work is associated with an increased risk for iatrogenic PTB and not with spontaneous PTB. Pregnancy-induced hypertension may play a role: when present, high physical work load leads to a more severe outcome.
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