Evidence map›Paper›PMID 33627376›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2021

IFNs Reset the Differential Capacity of Human Monocyte Subsets to Produce IL-12 in Response to Microbial Stimulation.

Alice Muglia Amancio, Lara Mittereder, Alexie Carletti, Kevin W Tosh, Daniel Green, Lis R Antonelli, Ricardo T Gazzinelli, Alan Sher, Dragana Jankovic

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Regulatory Effects of CD14Journal of immunology research · 2026
    Article
  3. Article
  4. The emerging role ofFrontiers in immunology · 2024
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Alice Muglia AmancioLaboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.ORCID 0000-0003-1098-8799
Lara MitterederLaboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
Alexie CarlettiLaboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
Kevin W ToshLaboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.ORCID 0000-0001-6236-8060
Daniel GreenWomen's Malignancies Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892.
Lis R AntonelliInstituto de Pesquisas Rene Rachou, FIOCRUZ, Belo Horizonte, Minas Gerais 30190-002, Brazil.ORCID 0000-0002-4969-8812
Ricardo T GazzinelliInstituto de Pesquisas Rene Rachou, FIOCRUZ, Belo Horizonte, Minas Gerais 30190-002, Brazil.
Alan SherLaboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.ORCID 0000-0001-7053-2895
Dragana JankovicLaboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892; djankovic@niaid.nih.gov.ORCID 0000-0001-7360-1809
National Institutes of Health · USInstituto de Ensino e Pesquisa Santa Casa · BRUniversity of Massachusetts Chan Medical School · US

Funding

Immune Regulation In Toxoplasmosis And Other Opportunistic InfectionsZIAAI000579 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI SHER, ALAN · 2009 to 2022
$7.8M
Intramural NIH HHS ZIA AI000579
6 · The paper itself

Abstract

Human primary monocytes are composed of a minor, more mature CD16

Indexed as

Cell DifferentiationCells, CulturedHumansInflammationInterferon-gammaInterleukin-12 Subunit p40Lipopolysaccharide ReceptorsMonocytesPrimary Cell CultureReceptors, IgGSignal TransductionTOR Serine-Threonine KinasesToxoplasmaToxoplasmosisTranscriptomeInterferon-gammaInterleukin-12 Subunit p40Lipopolysaccharide ReceptorsReceptors, IgGTOR Serine-Threonine Kinases

Identifiers

PMID33627376
PMCPMC8034562
OpenAlexW3131240217

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.