Evidence map›Paper›PMID 33627321›Full record

ArticleJournal of clinical microbiology2021

Performance of Four IgM Antibody Assays in the Diagnosis of Measles Virus Primary Infection and Cases with a Serological Profile Indicating Reinfection.

Georg Semmler, Stephan Walter Aberle, Hannah Griebler, Lukas Richter, Daniela Schmid, Karin Stiasny, Heidemarie Holzmann, Lukas Weseslindtner

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Seroprevalence against measles, Austria, stratified by birth years 1922 to 2024.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025
    Article
  4. Review
  5. MUW researcher of the month.Wiener klinische Wochenschrift · 2021
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Georg SemmlerCenter for Virology, Medical University of Vienna, Vienna, Austria.ORCID 0000-0002-0411-166X
Stephan Walter AberleCenter for Virology, Medical University of Vienna, Vienna, Austria.
Hannah GrieblerCenter for Virology, Medical University of Vienna, Vienna, Austria.
Lukas RichterDepartment of Surveillance and Infectious Disease Epidemiology, Austrian Agency for Health and Food Safety, Vienna, Austria.
Daniela SchmidDepartment of Surveillance and Infectious Disease Epidemiology, Austrian Agency for Health and Food Safety, Vienna, Austria.
Karin StiasnyCenter for Virology, Medical University of Vienna, Vienna, Austria.ORCID 0000-0002-1902-8674
Heidemarie HolzmannCenter for Virology, Medical University of Vienna, Vienna, Austria.
Lukas WeseslindtnerCenter for Virology, Medical University of Vienna, Vienna, Austria lukas.weseslindtner@meduniwien.ac.at.ORCID 0000-0001-8950-937X
Medical University of Vienna · ATAustrian Agency for Health and Food Safety · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The object of this study was to determine the diagnostic performance of four commercially available IgM tests in the diagnosis of measles virus (MeV) primary infection and cases with a serological profile indicating reinfection. Sera from 187 patients with MeV primary infection, 30 patients with suspected reinfection (after vaccine failure), and 153 patients with rash-like symptoms after exclusion of MeV infection were retested with four IgM tests. MeV infection was verified by reverse transcriptase PCR (RT-PCR), and primary and suspected reinfections were differentiated by IgG avidity and neutralization assays. All IgM assays displayed significant agreement (Cohen's κ, ≥0.604; all

Indexed as

MeaslesMeasles virusAntibodies, ViralAntibody AffinityHumansImmunoglobulin MReinfectionSensitivity and SpecificityAntibodies, ViralImmunoglobulin MantibodiesIgMimmunoassaymeaslesMeVreinfection

Identifiers

PMID33627321
PMCPMC8091831
OpenAlexW3130249507

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.