Evidence map›Paper›PMID 33627188›Full record

SynthesisVeterinary research2021

Diagnosis of tuberculosis in wildlife: a systematic review.

Jobin Thomas, Ana Balseiro, Christian Gortázar, María A Risalde

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Veterinary research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 89 citations in OpenAlex.

  1. Article
  2. First Report ofAnimals : an open access journal from MDPI · 2026
    Article
  3. Article
  4. Article
  5. Mycobacterium tuberculosis complex species-induced infections in dogs: a narrative review of five cases reported in Brazil (1990-2024).Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. B Cell and Antibody Responses in Bovine Tuberculosis.Antibodies (Basel, Switzerland) · 2024
    Review
  13. Article
  14. Article
  15. Congenital feline tuberculosis: the first case report.Veterinary research forum : an international quarterly journal · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. Will we ever eradicate animal tuberculosis?Irish veterinary journal · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Jobin ThomasSanidad Y Biotecnología (SaBio), Instituto de Investigación en Recursos Cinegéticos IREC (UCLM-CSIC), 13003, Ciudad Real, Spain.
Ana BalseiroDepartamento de Sanidad Animal, Facultad de Veterinaria, Universidad de León, 24071, León, Spain. abalm@unileon.es.ORCID http://orcid.org/0000-0002-5121-7264
Christian GortázarSanidad Y Biotecnología (SaBio), Instituto de Investigación en Recursos Cinegéticos IREC (UCLM-CSIC), 13003, Ciudad Real, Spain.
María A RisaldeDepartamento de Anatomía Y Anatomía Patológica Comparadas Y Toxicología. Facultad de Veterinaria, Universidad de Córdoba (UCO), 14014, Córdoba, Spain.
Indian Council of Agricultural Research · INInstituto de Ganadería de Montaña · ESInstituto de Investigación en Recursos Cinegéticos · ESInstituto Maimónides de Investigación Biomédica de Córdoba · ES

Funding

Agencia Estatal de Investigación CGL2017-89866 (MINECO, Spain and EU FEDER)Agencia Estatal de Investigación RTI2018-096010-B-C21 (AEI, MCIU and FEDER co-funded)Gobierno del Principado de Asturias PCTI 2018-2020 (GRUPIN: IDI2018-000237)Indian Council of Agriculture Research (IN) Fellowship 2014-15 (ICAR-IF 2014-15)Junta de Comunidades de Castilla-La Mancha MYCOTRAINING SBPLY/19/180501/000174
6 · The paper itself

Abstract

Animal tuberculosis (TB) is a multi-host disease caused by members of the Mycobacterium tuberculosis complex (MTC). Due to its impact on economy, sanitary standards of milk and meat industry, public health and conservation, TB control is an actively ongoing research subject. Several wildlife species are involved in the maintenance and transmission of TB, so that new approaches to wildlife TB diagnosis have gained relevance in recent years. Diagnosis is a paramount step for screening, epidemiological investigation, as well as for ensuring the success of control strategies such as vaccination trials. This is the first review that systematically addresses data available for the diagnosis of TB in wildlife following the Preferred Reporting Items of Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The article also gives an overview of the factors related to host, environment, sampling, and diagnostic techniques which can affect test performance. After three screenings, 124 articles were considered for systematic review. Literature indicates that post-mortem examination and culture are useful methods for disease surveillance, but immunological diagnostic tests based on cellular and humoral immune response detection are gaining importance in wildlife TB diagnosis. Among them, serological tests are especially useful in wildlife because they are relatively inexpensive and easy to perform, facilitate large-scale surveillance and can be used both ante- and post-mortem. Currently available studies assessed test performance mostly in cervids, European badgers, wild suids and wild bovids. Research to improve diagnostic tests for wildlife TB diagnosis is still needed in order to reach accurate, rapid and cost-effective diagnostic techniques adequate to a broad range of target species and consistent over space and time to allow proper disease monitoring.

Indexed as

Animals, WildAnimalsDisease ReservoirsMycobacterium bovisMycobacterium tuberculosisTuberculosisanimal tuberculosisdiagnosisimmunological methodsMycobacterium tuberculosis complexPRISMAsystematic reviewwildlife

Identifiers

PMID33627188
PMCPMC7905575
OpenAlexW3130379153

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.