Evidence map›Paper›PMID 33627153›Full record

Observational studyJournal of orthopaedic surgery and research2021

The impact of COVID-19 on the management and outcomes of patients with proximal femoral fractures: a multi-centre study of 580 patients.

Alice Wignall, Vasileios Giannoudis, Chiranjit De, Andrea Jimenez, Simon Sturdee, Sohail Nisar, Hemant Pandit, Aashish Gulati, Jeya Palan

Registry-linked trialOpen access · goldAbstract readComparative StudyMulticenter StudyObservational Study
In one paragraph

Observational study in Journal of orthopaedic surgery and research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05133648 (Association of Anesthesia Technique With Morbidity and Mortality in Patients With COVID-19 and Surgery for Hip Fracture), which is not on this map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
3.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05133648 unknown statusnot on this mapstarted 2023, after this paper: background citation

Association of Anesthesia Technique With Morbidity and Mortality in Patients With COVID-19 and Surgery for Hip Fracture: a Retrospective Population Cohort Study

TypeobservationalSponsorUniversity of British ColumbiaRan2023 to 2023Enrolled1,000ConditionsHip Fractures, COVID-19, General Anesthesia, Spinal AnesthesiaArmsHip Fracture Surgery, COVID-19 infection
3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Orthopaedic, trauma surgery, and Covid-2019 pandemic: clinical panorama and future prospective in Europe.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022
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  16. Surgical treatment for fragility hip fractures during the COVID-19 pandemic resulted in lower short-term postoperative functional outcome and a higher complication rate compared to the pre-pandemic period.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Alice WignallLeeds Teaching Hospitals NHS Trust, Leeds, UK. alice.wignall@nhs.net.ORCID http://orcid.org/0000-0002-6744-2650
Vasileios GiannoudisHuddersfield Royal Infirmary, Huddersfield, UK.
Chiranjit DeSandwell & West Birmingham Hospitals NHS Trust, Lyndon, UK.
Andrea JimenezHuddersfield Royal Infirmary, Huddersfield, UK.
Simon SturdeeHuddersfield Royal Infirmary, Huddersfield, UK.
Sohail NisarLeeds Teaching Hospitals NHS Trust, Leeds, UK.
Hemant PanditLeeds Teaching Hospitals NHS Trust, Leeds, UK.
Aashish GulatiSandwell & West Birmingham Hospitals NHS Trust, Lyndon, UK.
Jeya PalanLeeds Teaching Hospitals NHS Trust, Leeds, UK.
Leeds Teaching Hospitals NHS Trust · GBHuddersfield Royal Infirmary · GBSandwell & West Birmingham Hospitals NHS Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOn the 11th March 2020, the World Health Organization declared the COVID-19 outbreak a pandemic. Multiple new guidelines were proposed and existing models of social, domestic and hospital care altered. Most healthcare systems were largely unprepared for this, and the pandemic has tested their adaptability. This study aimed to assess the impact of COVID-19 on the demographics, presentation, clinical management and outcomes of patients with proximal femoral (hip) fractures comparing them to a similar cohort of patients admitted a year earlier.

methodsThis retrospective multi-centre cohort study compared all patients admitted with hip fractures between 1st March and 30th May 2019 (group PC: pre-COVID-19) with hip fracture patients admitted over the same time period during the pandemic in 2020 (group C: COVID-19). The data was obtained from the hospitals' local and National Hip Fracture Databases. Mortality data was checked with the Office for National Statistics (ONS). Primary outcomes were time to theatre, in-patient length of stay and 30-day mortality.

resultsA total of 580 patients were included (304 group PC, 276 group C). Patient demographics including Charlson Comorbidity Index and Nottingham Hip Fracture Scores were broadly similar across the two cohorts. There was a significant reduction in the percentage of total hip replacements (11 to 5%, p = 0.006) in group C. There was an increase in conservative management (1 to 5%, p = 0.002) in group C. Time to theatre was significantly delayed in group C (43.7 h) vs group PC (34.6 h) (p ≤ 0.001). The overall length of hospital stay was significantly longer in group PC (16.6 days) vs group C (15 days) (p = 0.025). The 30-day mortality rate in group C was 9.8% compared to 8.2% in group PC (p = 0.746), but for COVID-19 (+) patients, it was significantly higher at 38.2% vs 5.8% in COVID-19 (-) patients (p < 0.001).

conclusionThis is one of the largest multi-centre comparative cohort study in the literature to date examining the impact of the COVID-19 pandemic on the management of hip fracture patients. Whilst mortality rates were similar in both groups, COVID-19-positive patients were almost seven times more likely to die, reflecting the seriousness of the COVID-19 infection and its sequelae in such elderly, vulnerable patients.

Indexed as

COVID-19PandemicsAgedAged, 80 and overArthroplasty, Replacement, HipFemaleHemiarthroplastyHip FracturesHumansMaleRetrospective Studies30-day mortalityCOVID-19Extracapsular hip fractureIntracapsular hip fractureLength of stayProximal femoral (hip) fractureTime to theatre

Identifiers

PMID33627153
PMCPMC7903025
OpenAlexW3131644614

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.