Evidence map›Paper›PMID 33626483›Full record

ArticleAddictive behaviors2021

Sexual orientation and gender identity disparities in co-occurring depressive symptoms and probable substance use disorders in a national cohort of young adults.

Jennifer K Felner, Sean J Haley, Hee-Jin Jun, Jennifer P Wisdom, Laura Katuska, Heather L Corliss

Open access · hybridAbstract read
In one paragraph

Article in Addictive behaviors, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Intersecting Identities Among Hispanic Sexual Minority Youth and Their Relationship With Substance Use and Depressive Symptoms.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Trajectories of Drug Use and Depressive Symptoms among Latinx Youth and Sexual Minority Youth.International journal of environmental research and public health · 2023
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Risk of Substance Use Among LGBTQI+ Community Affected by Lifetime and Day-to-day Discrimination - Results from a Cross-sectional Study Performed in South India.Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Jennifer K FelnerSan Diego State University, School of Public Health, Institute for Behavioral and Community Health, Center for Research on Sexuality and Sexual Health, 9245 Sky Park Court, Suite 224, San Diego, CA 92123, United States. Electronic address: Jfelner@sdsu.edu.
Sean J HaleyDepartment of Health Policy and Management, City University of New York's Graduate School of Public Health and Health Policy, 55 West 125(th) St, NY, NY 10027, United States.
Hee-Jin JunSan Diego State University, School of Public Health, Institute for Behavioral and Community Health, Center for Research on Sexuality and Sexual Health, 9245 Sky Park Court, Suite 224, San Diego, CA 92123, United States.
Jennifer P WisdomWisdom Consulting, 1133 Broadway #1205, NY, NY 10010, United States.
Laura KatuskaDepartment of Nutrition, Harvard T.H. Chan School of Public Health, 655 Huntington Avenue, Boston, MA 02115, United States.
Heather L CorlissSan Diego State University, School of Public Health, Institute for Behavioral and Community Health, Center for Research on Sexuality and Sexual Health, 9245 Sky Park Court, Suite 224, San Diego, CA 92123, United States.
San Diego State University · USCity University of New York · USHarvard University · US

Funding

Training Program in Substance Use, HIV and Related InfectionsT32DA023356 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Natasha Martin, Steffanie A Strathdee · 2007 to 2026
$7.8M
Substance Disorders, Substance Use Treatment, and Sexual Orientation in YouthR01DA033974 · NIDA · BRIGHAM AND WOMEN'S HOSPITAL · PI CORLISS, HEATHER L · 2013 to 2017
$3.5M
Adolescent Substance Use and the Transition to Adulthood in Sexual Minority YouthK01DA023610 · NIDA · BOSTON CHILDREN'S HOSPITAL · PI CORLISS, HEATHER L · 2007 to 2011
$689k
NIDA NIH HHS K01 DA023610NIDA NIH HHS R01 DA033974NIDA NIH HHS T32 DA023356
6 · The paper itself

Abstract

This study examined sexual orientation and gender identity differences in co-occurring depressive symptoms and substance use disorders (SUDs) among young adults in the Growing Up Today Study national cohort (n = 12,347; ages 20-35; 93% non-Hispanic white). Self-administered questionnaires assessed recent co-occurring depressive symptoms and probable nicotine dependence, alcohol use disorder, and drug use disorder. Multinomial logistic regressions with generalized estimating equations quantified differences in prevalences of depressive symptoms only, SUDs only, and co-occurrence, among sexual minorities (mostly heterosexual; lesbian, gay, and bisexual [LGB]) compared to completely heterosexual participants, and gender minorities compared to cisgender participants. Analyses stratified by sex assigned at birth revealed sexual minorities evidenced greater odds of co-occurrence than their completely heterosexual counterparts (assigned female AORs: 3.11-9.80, ps < 0.0001; assigned male AORs: 2.90-4.87, ps < 0.001). Sexual orientation differences in co-occurrence were pronounced among LGB participants assigned female at birth who evidenced nearly 10 times the odds of co-occurring depressive symptoms with nicotine dependence and drug use disorders than did heterosexual participants assigned female at birth. Relationships between gender identity and co-occurrence were generally weaker, possibly due to low power. Gender minorities assigned male at birth, however, evidenced greater odds of co-occurring depressive symptoms and alcohol use disorders (AOR 2.75, p = 0.013) than their cisgender counterparts. This study adds to the limited research quantifying sexual orientation or gender identity differences in recent co-occurring depressive symptoms and SUDs among young adults and suggests sexual and gender minority young adults should be prioritized in prevention and treatment of co-occurring depression and SUDs.

Indexed as

AlcoholismSubstance-Related DisordersAdultDepressionFemaleGender IdentityHeterosexualityHumansMaleSexual BehaviorYoung AdultCo-occurring disordersDepressionLGBTQMinority stressSexual and gender minoritiesSubstance use disorders

Identifiers

PMID33626483
PMCPMC8012013
OpenAlexW3118528951

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.