Evidence map›Paper›PMID 33626214›Full record

ArticleCancer medicine2021

Prostate-specific antigen testing among young men: an opportunity to improve value.

Suzanne M Lange, Jacob P Ambrose, Michael C Flynn, William T Lowrance, Heidi A Hanson, Brock B O'Neil

Abstract read
In one paragraph

Article in Cancer medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Suzanne M LangeDivision of Urology, University of Utah, Salt Lake City, UT, USA.ORCID 0000-0003-4000-819X
Jacob P AmbroseDepartments of Surgery and Population Sciences, University of Utah, Salt Lake City, UT, USA.
Michael C FlynnDepartment of Internal Medicine, University of Utah Health, Salt Lake City, UT, USA.
William T LowranceDivision of Urology, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.
Heidi A HansonDepartments of Surgery and Population Sciences, University of Utah, Salt Lake City, UT, USA.
Brock B O'NeilDivision of Urology, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.

Funding

Competition, Bundled Care Payment, and Low-Value Cancer CareK08CA234431 · NCI · UNIVERSITY OF UTAH · PI O'NEIL, BROCK · 2019 to 2023
$1.3M
NCI NIH HHS K08 CA234431NIH HHS K08CA234431
6 · The paper itself

Abstract

introductionProstate cancer screening using prostate-specific antigen (PSA) testing remains widespread. The prevalence of PSA testing in young men is unknown and may be an appropriate target for improving health care by decreasing low-value testing in this age group. The purpose of this study was to determine PSA testing rates in men younger than current guidelines support. MATERIALS AND

methodsHealth Informational National Trends Surveys (HINTS) from 2011 to 2014 and 2017 were analyzed to establish the prevalence of PSA testing in young men and to evaluate the differences in testing rates based on race.

resultsThe combined survey data included 5178 men, with 2393 reporting previous PSA screening. Of men ages 18-39, 7% recalled receipt of PSA testing. Twenty-two percent of men between the ages of 40 and 44 had been tested. Among men under age 40, PSA testing was more common among black men (14%) compared to white men (7%), Hispanics (6%), and men of Asian descent (8%). Logistic regression modeling demonstrates that black men under the age of 40 were more likely to undergo PSA testing than other racial or ethnic groups (odds ratio 2.14; 95% CI 1.17, 3.93).

conclusionsCurrent guidelines do not recommend routine PSA testing in average-risk men under the age of 40. This study found that a significant number of young men are exposed to testing, with the greatest risk among black men. This suggests that there is an opportunity to improve the value of PSA testing by decreasing testing in young men.

Indexed as

AdultAgedAge FactorsAsian PeopleBlack PeopleConfidence IntervalsHispanic or LatinoHumansLogistic ModelsMaleMiddle AgedOdds RatioPractice Guidelines as TopicProstate-Specific AntigenProstatic NeoplasmsSurveys and QuestionnairesProstate-Specific Antigenbiomarkerscancer educationclinical guidelinesprostate cancerscreeningurological oncology

Identifiers

PMID33626214
PMCPMC7957163

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.