Evidence map›Paper›PMID 33626002›Full record

ArticleThe Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology2020

Infections developing in patients undergoing liver transplantation: Recipients of living donors may be more prone to bacterial/fungal infections.

Tansu Yamazhan, Cansu Bulut Avşar, Murat Zeytunlu, Meltem Taşbakan, Rüçhan Sertöz, Ayşın Zeytinoğlu, Şöhret Aydemir, Ömer Ünalp, Orkan Ergün, Alper Uğuz and 10 more

Open access · greenAbstract readEvaluation Study
In one paragraph

Article in The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 1 institution in 1 country.

Tansu YamazhanDepartment of Infectious Diseases and Clinical Microbiology, Ege University School of Medicine, Bornova, Izmir, Turkey.
Cansu Bulut AvşarDepartment of Infectious Diseases and Clinical Microbiology, Ege University School of Medicine, Bornova, Izmir, Turkey.
Murat ZeytunluDepartment of General Surgery, Ege University School of Medicine, Bornova, Izmir, Turkey.
Meltem TaşbakanDepartment of Infectious Diseases and Clinical Microbiology, Ege University School of Medicine, Bornova, Izmir, Turkey.
Rüçhan SertözDepartment of Medical Microbiology, Ege University School of Medicine, Bornova, Izmir, Turkey.
Ayşın ZeytinoğluDepartment of Medical Microbiology, Ege University School of Medicine, Bornova, Izmir, Turkey.
Şöhret AydemirDepartment of Medical Microbiology, Ege University School of Medicine, Bornova, Izmir, Turkey.
Ömer ÜnalpDepartment of General Surgery, Ege University School of Medicine, Bornova, Izmir, Turkey.
Orkan ErgünDepartment of Pediatric Surgery, Ege University School of Medicine, Bornova, Izmir, Turkey.
Alper UğuzDepartment of General Surgery, Ege University School of Medicine, Bornova, Izmir, Turkey.
Funda ÖzgençDivision of Paediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Ege University School of Medicine, Bornova, Izmir, Turkey.
Fulya GünşarDepartment of Gastroenterology, Ege University School of Medicine, Bornova, Izmir, Turkey.
İlker TuranDepartment of Gastroenterology, Ege University School of Medicine, Bornova, Izmir, Turkey.
Sezgin UlukayaDepartment of Anaesthesiology and Reanimation, Ege University School of Medicine, Bornova, Izmir, Turkey.
Nuri DenizDepartment of Anaesthesiology and Reanimation, Ege University School of Medicine, Bornova, Izmir, Turkey.
Funda YilmazDepartment of Pathology, Ege University School of Medicine, Bornova, Izmir, Turkey.
Deniz NartDepartment of Pathology, Ege University School of Medicine, Bornova, Izmir, Turkey.
Ezgi GülerDepartment of Radiology, Ege University School of Medicine, Bornova, Izmir, Turkey.
Kutsal TurhanDirector of Transplantation Council, Ege University School of Medicine, Izmir, Turkey.
Zeki KarasuDepartment of Gastroenterology, Ege University School of Medicine, Bornova, Izmir, Turkey.
Ege University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsDespite surgical advances in liver transplantation and effective prophylactic strategies, posttransplant infections are the most important cause of morbidity and mortality. Diagnosis and management of infections because of developing immunosuppression is difficult and adversely affects mortality. This study aimed to review bacterial and fungal infections in patients after liver transplantation and to reveal the resistance rates. MATERIALS AND

methodsA total of 107 patients who underwent liver transplantation between January 2017 and February 2018 were evaluated retrospectively with regard to demographic characteristics, causes of transplantation, conditions that may lead to infection, postoperative infections, pathogens, and resistance patterns.

resultsOf the 107 patients who underwent liver transplantation, 48 (44.8%) had an infection. Bacterial infections were detected in 41% of the patients, and fungal infections were found in 13%. When we compared living and cadaveric transplants in terms of infection development, these rates were found to be 53% and 33%, respectively (p=0.034). No statistically significant results could be obtained when evaluating conditions such as sex, presence of underlying primary disease, Model for End-Stage Liver Disease MELD score, diabetes status, total parenteral nutrition, and risk factors for infection.

conclusionAfter liver transplantation, infections are often seen in the first month of the postoperative period. Knowing the most common pathogens and resistance states in this process reduces infection-related deaths by providing appropriate treatment regimens at the right time.

Indexed as

AdolescentAdultAgedBacterial InfectionsEnd Stage Liver DiseaseFemaleHumansImmunosuppression TherapyLiver TransplantationLiving DonorsMaleMiddle AgedMycosesPostoperative ComplicationsRetrospective StudiesRisk Factors

Identifiers

PMID33626002
PMCPMC7928243
OpenAlexW3022375968

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.