Evidence map›Paper›PMID 33625618›Full record

ArticleJournal of autism and developmental disorders2022

Perinatal Factors in Newborn Are Insidious Risk Factors for Childhood Autism Spectrum Disorders: A Population-based Study.

Inn-Chi Lee, Yu-Hsun Wang, Jeng-Yuan Chiou, James Cheng-Chung Wei

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of autism and developmental disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Association between paternal age at childbirth and autism spectrum disorder in offspring.Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2022
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Inn-Chi LeeDivision of Pediatric Neurology, Department of Pediatrics, Chung Shan Medical University Hospital, Taichung, Taiwan.ORCID http://orcid.org/0000-0001-9192-8848
Yu-Hsun WangDepartment of Medical Research, Chung Shan Medical University Hospital, Taichung, Taiwan.
Jeng-Yuan ChiouSchool of Health Policy and Management, Chung Shan Medical University, No.110, Sec.1, Jianguo N. Rd, Taichung City, 40201, Taiwan. tom@csmu.edu.tw.
James Cheng-Chung WeiDepartment of Allergy, Immunology & Rheumatology, Chung Shan Medical University Hospital and Graduate Institute of Integrated Medicine, China Medical University, Taichung, Taiwan. jccwei@gmail.com.
Chung Shan Medical University Hospital · TWChina Medical University · TWChung Shan Medical University · TW

Funding

Chung Shan Medical University Hospital CSH-2015-A-009Chung Shan Medical University Hospital CSH-2021-C012
6 · The paper itself

Abstract

We analyzed claims data from the Taiwan National Health Insurance database, which contains data of 23.5 million Taiwan residents. We included children born after January 1, 2000 who had received a diagnosis of autism spectrum disorders (ASD). Patients who were not diagnosed with ASD were included in the control group. The ASD prevalence was 517 in 62,051 (0.83%) children. Neonatal jaundice, hypoglycemia, intrauterine growth retardation (IUGR), and craniofacial anomalies (CFA) differed significantly between the ASD and control groups. After logistic regressive analysis, the adjusted odds ratios of IUGR, CFA, neonatal hypoglycemia, and neonatal jaundice were 8.58, 7.37, 3.83, and 1.32, respectively. Those insidiously perinatal risk factors, namely CFA, IUGR, neonatal hypoglycemia, and neonatal jaundice, could increase the risk of ASD.

Indexed as

Autism Spectrum DisorderCase-Control StudiesChildFemaleHumansInfant, NewbornOdds RatioPregnancyRisk FactorsTaiwanAutismCraniofacial anomaliesHypoglycemiaIntrauterine growth retardationNeonatal jaundice

Identifiers

PMID33625618
OpenAlexW3130020020

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.