Evidence map›Paper›PMID 33625601›Full record

ArticleArchives of osteoporosis2021

The serum 25(OH)D level and hand grip strength for fall risk assessment among osteoporotic elderly Japanese women.

Takashi Nagai, Ichiro Okano, Koji Ishikawa, Takuma Kuroda, Yusuke Oshita, Koki Tsuchiya, Soji Tani, Hiroki Okamura, Keizo Sakamoto, Katsunori Inagaki

Open access · hybridAbstract read
In one paragraph

Article in Archives of osteoporosis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Takashi NagaiDepartment of Orthopaedic Surgery, Showa University School of Medicine, 1-5-8 Hatanodai, Sinagaka-ku, Tokyo, 142-8666, Japan. ppp4989@med.showa-u.ac.jp.ORCID https://orcid.org/0000-0002-8815-1182
Ichiro OkanoDepartment of Orthopaedic Surgery, Showa University School of Medicine, 1-5-8 Hatanodai, Sinagaka-ku, Tokyo, 142-8666, Japan.ORCID https://orcid.org/0000-0003-1741-5176
Koji IshikawaDepartment of Orthopaedic Surgery, Showa University School of Medicine, 1-5-8 Hatanodai, Sinagaka-ku, Tokyo, 142-8666, Japan.ORCID https://orcid.org/0000-0003-3689-5662
Takuma KurodaDepartment of Orthopaedic Surgery, Showa University School of Medicine, 1-5-8 Hatanodai, Sinagaka-ku, Tokyo, 142-8666, Japan.
Yusuke OshitaDepartment of Orthopaedic Surgery, Showa University School of Medicine, 1-5-8 Hatanodai, Sinagaka-ku, Tokyo, 142-8666, Japan.
Koki TsuchiyaDepartment of Orthopaedic Surgery, Showa University School of Medicine, 1-5-8 Hatanodai, Sinagaka-ku, Tokyo, 142-8666, Japan.
Soji TaniDepartment of Orthopaedic Surgery, Showa University School of Medicine, 1-5-8 Hatanodai, Sinagaka-ku, Tokyo, 142-8666, Japan.
Hiroki OkamuraDepartment of Orthopaedic Surgery, Showa University School of Medicine, 1-5-8 Hatanodai, Sinagaka-ku, Tokyo, 142-8666, Japan.
Keizo SakamotoDepartment of Orthopaedic Surgery, Showa University School of Medicine, 1-5-8 Hatanodai, Sinagaka-ku, Tokyo, 142-8666, Japan.
Katsunori InagakiDepartment of Orthopaedic Surgery, Showa University School of Medicine, 1-5-8 Hatanodai, Sinagaka-ku, Tokyo, 142-8666, Japan.
Showa University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated the relationship between serum 25(OH)D levels, grip strength, and fall score in elderly osteoporotic women for fall risk assessment. Both low serum 25(OH)D and low grip strength were independently associated with increased fall risk. The serum 25(OH)D cutoff specific to increased fall risk was 14 mg/dL (35 nmol/L). PURPOSE: This study aimed to establish a cutoff value of serum 25-hydroxyvitamin D (25(OH)D) for fall assessment and investigate the relationship between serum 25(OH)D, grip strength, and fall score adjusted for age in osteoporotic elderly Japanese women.

methodsThis is a cross-sectional study utilizing collected data of osteoporotic elderly (age ≥65 years) female patients. A questionnaire for fall risk assessment was used, in which a score ≥ 6 was determined as increased fall risk. Serum 25(OH)D levels and grip strength were measured, and the cutoff points were calculated by receiver operating curve (ROC) analysis. Logistic regression analysis with age adjustment was conducted for potential risk factors for fall.

resultsAfter applying eligibility criteria, finally, 349 patients were enrolled. The median patient age was 77.0 years, and the mean serum 25(OH)D level was 15.6 ng/mL (36 nmol/L). Based on the ROC analysis, we defined the cutoff values of serum 25(OH)D level and grip strength as 14 ng/mL (35 nmol/L) and 15 kg, respectively. A multivariate analysis adjusted for age was conducted. Low serum 25(OH)D level and grip strength were independent risk factors for ≥6 fall risk scores.

conclusionBoth low serum 25(OH)D level and low grip strength were independently associated with increased fall risk score in osteoporotic elderly women. The appropriate serum 25(OH)D cutoff specific to the increased fall risk group in this population was 14 mg/dL (35 nmol/L). These findings might be used for the identification of patients with high fall risks. These results should be confirmed in other patient groups.

Indexed as

Hand StrengthVitamin D DeficiencyAgedCross-Sectional StudiesFemaleHumansJapanRisk AssessmentVitamin D25-hydroxyvitamin DVitamin D25(OH)DFall scoreGrip strengthOsteoporosisSarcopeniaVitamin D

Identifiers

PMID33625601
PMCPMC7904705
OpenAlexW3133034771

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.