Evidence map›Paper›PMID 33625209›Full record

ArticleACS sensors2021

A DNA-Based MRI Contrast Agent for Quantitative pH Measurement.

Hyewon Seo, Kristine Y Ma, Erin E Tuttle, Isen Andrew C Calderon, Alissa D Buskermolen, Chris A Flask, Heather A Clark

Abstract read
In one paragraph

Article in ACS sensors, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hyewon SeoDepartment of Bioengineering, Northeastern University, Boston, Massachusetts 02115, United States.ORCID 0000-0001-8248-3947
Kristine Y MaDepartment of Bioengineering, Northeastern University, Boston, Massachusetts 02115, United States.ORCID 0000-0003-1955-0515
Erin E TuttleDepartment of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, United States.ORCID 0000-0003-4704-8960
Isen Andrew C CalderonDepartment of Bioengineering, Northeastern University, Boston, Massachusetts 02115, United States.ORCID 0000-0001-8910-1083
Alissa D BuskermolenDepartment of Bioengineering, Northeastern University, Boston, Massachusetts 02115, United States.
Chris A FlaskDepartments of Radiology, Biomedical Engineering, and Pediatrics, Case Western Reserve University, Cleveland, Ohio 44106, United States.
Heather A ClarkDepartment of Bioengineering, Northeastern University, Boston, Massachusetts 02115, United States.ORCID 0000-0002-2628-9194

Funding

AChMRNS: Nanosensors for Chemical Imaging of Acetylcholine Using MRIUF1NS107713 · NINDS · NORTHEASTERN UNIVERSITY · PI CLARK, HEATHER A, FLASK, CHRISTOPHER A · 2018 to 2018
$1.6M
NINDS NIH HHS UF1 NS107713
6 · The paper itself

Abstract

Extracellular pH is important in clinical measurements due to its correlation to cell metabolism and disease progression. In MRI,

Indexed as

Contrast MediaNanoparticlesGadoliniumHumansHydrogen-Ion ConcentrationMagnetic Resonance ImagingContrast MediaGadoliniumbioimagingDNA dendrimerDNA nanostructureMRI contrast agentpH quantification

Identifiers

PMID33625209
PMCPMC9489053

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.