Evidence map›Paper›PMID 33624759›Full record

ArticleBiology of reproduction2021

Cyclic AMP links luteinizing hormone signaling to dephosphorylation and inactivation of the NPR2 guanylyl cyclase in ovarian follicles†.

Jeremy R Egbert, Jerid W Robinson, Tracy F Uliasz, Lincoln R Potter, Laurinda A Jaffe

Open access · bronzeAbstract read
In one paragraph

Article in Biology of reproduction, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Intercellular diffusion of cyclic nucleotides followed by gap junction closure restarts meiosis in mouse preovulatory follicles.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. Regulation of oocyte maturation: Role of conserved ERK signaling.Molecular reproduction and development · 2022
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jeremy R EgbertDepartment of Cell Biology, Univ. of Connecticut Health Center, Farmington, CT, USA.
Jerid W RobinsonDepartment of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, MN, USA.
Tracy F UliaszDepartment of Cell Biology, Univ. of Connecticut Health Center, Farmington, CT, USA.
Lincoln R PotterDepartment of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, MN, USA.
Laurinda A JaffeDepartment of Cell Biology, Univ. of Connecticut Health Center, Farmington, CT, USA.
UConn Health · USUniversity of Minnesota · US

Funding

Signal Transduction at FertilizationR37HD014939 · NICHD · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI JAFFE, LAURINDA A. · 2014 to 2023
$4.8M
SIGNAL TRANSDUCTIONS AT FERTILIZATIONR01HD014939 · NICHD · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI JAFFE, LAURINDA A. · 1985 to 2012
$2.8M
NICHD NIH HHS R01 HD014939NICHD NIH HHS R37 HD014939
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Signal TransductionAnimalsAtrial Natriuretic Factor Receptor BCyclic AMPFemaleGene SilencingLuteinizing HormoneMiceOvarian FolliclePhosphorylationReceptors, Atrial Natriuretic FactorAtrial Natriuretic Factor Receptor BCyclic AMPLuteinizing HormoneReceptors, Atrial Natriuretic Factorcyclic AMPcyclic GMPforskolinluteinizing hormonemouse preovulatory folliclenatriuretic peptide receptor

Identifiers

PMID33624759
PMCPMC8111234
OpenAlexW3130256566

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.