Evidence map›Paper›PMID 33624600›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2021

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C Zhou, X Zheng, X Huang, J Su, M Li, Z Chen, M Li, H Chi

Open access · greenAbstract read
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. [Therapeutic mechanism ofNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2024
    Article
  2. Article
  3. [Changes in percentage of GATA3Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2023
    Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

C ZhouFirst Clinical Medical College, Guangdong Medical University, Zhanjiang 524023, China.
X ZhengSchool Of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
X HuangSchool Of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
J SuResearch Laboratory, Foshan Women and Children's Hospital, Affiliated Foshan Women and Children's Hospital of Southern Medical University, Foshan 528000, China.
M LiSchool Of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
Z ChenDongguan Mathematical Engineering Academy of Chinese Medicine, Guangzhou University Chinese Medicine, Dongguan 523000, China.
M LiSchool Of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
H ChiSecond School of Clinical Medicine, Guangdong Medical University, Dongguan 523000, China.
Guangzhou University of Chinese Medicine · CNGuangdong Medical College · CNDongguan University of Technology · CNFoshan Maternity and Child Health Care Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the effect of

objectiveMale Balb/c mice were randomly divided into control group, DSS group, mesalazine group (ME, 400 mg/kg), and 2.275 g/kg, 4.55 g/kg and 9.1 g/kg HQD groups. All the mice were given free access to normal chow. Except for those in the normal control group, all the mice were given 3% DSS solution for 7 days to establish models of UC. The mice in ME group and 3 HQD groups were given mesalazine or HQD via oral gavage at the specified doses once a day. Flow cytometry was performed to analyze the ILC3s, MHC Ⅱ, Th1 and Treg in the lamina propria lymphocytes in the colon. Milliplex was performed to determine cytokine levels of in the colon tissues.

objectiveCompared with those in DSS group, the mice in the 3 HQD groups all showed obviously lessened symptoms of UC with significantl decreased DAI score (

objectiveHQD alleviates DSS- induced UC in mice by increasing ILC3s and MHC Ⅱ expression to suppress the function of Th17 and Th1 cells and promote Treg and Th2 cells.

Indexed as

Colitis, UlcerativeAnimalsCell CountImmunity, InnateMaleMesalamineMiceScutellaria baicalensisMesalaminehelper T cellsHuangqin decoctioninnate lymphoid cellsulcerative colitis

Identifiers

PMID33624600
PMCPMC7905254
OpenAlexW3131853610

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.