Evidence map›Paper›PMID 33624593›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2021

[MiR-600 suppresses HeLa cell proliferation by inhibiting hypoxia-inducible factor-1

X Zhou, J Deng, W Zhang, J Wang

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. [Overexpression of miR-607 inhibits hepatocellular carcinoma cell growth and metastasis by down-regulating TRPC5].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

X ZhouDepartment of Obstetrics and Gynecology, Chengdu Second People's Hospital, Chengdu 610000, China.
J DengDepartment of Obstetrics and Gynecology, First Affiliated Hospital of Chengdu Medical College, Chengdu 610000, China.
W ZhangDepartment of Respiratory Medicine, First Affiliated Hospital of Chengdu Medical College, Chengdu 610000, China.
J WangDepartment of Rheumatology Medicine, Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.
First Affiliated Hospital of Chengdu Medical College · CNChengdu Second People's Hospital · CNDalian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine whether miR-600 suppresses the proliferation of HeLa cells by inhibiting hypoxia-inducible factor-1

objectiveHeLa cells were transfected with miR-600 mimic and plasmid-HIF-1

objectiveThe viability of HeLa cells showed no obvious changes 6 h after transfection with miR-600 mimic or Plasmid-HIF-1

objectivemiR-600 suppresses the proliferation of HeLa cells and down-regulate the expressions of cyclin D1 and VEGF by inhibiting HIF-1

Indexed as

Hypoxia-Inducible Factor 1, alpha SubunitMicroRNAsCell ProliferationHeLa CellsHumansSignal TransductionVascular Endothelial Growth Factor AHypoxia-Inducible Factor 1, alpha SubunitMicroRNAsMIRN600 microRNA, humanVascular Endothelial Growth Factor Acell proliferationHeLa cellshypoxia-inducible factor-1αmiR-600vascular endothelial growth factor

Identifiers

PMID33624593
PMCPMC7905238
OpenAlexW3132098163

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.