Evidence map›Paper›PMID 33624188›Full record

ArticleMagma (New York, N.Y.)2021

EGFR-specific single-chain variable fragment antibody-conjugated Fe

Yuan Lu, Jing Huang, Fakai Li, Yuan Wang, Ming Ding, Jian Zhang, Hong Yin, Rui Zhang, Xinling Ren

Open access · bronzeAbstract read
In one paragraph

Article in Magma (New York, N.Y.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 27 citations in OpenAlex.

  1. Long-Term Biodistribution of FeInternational journal of molecular sciences · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Gold Nanoparticles Contact with Cancer Cell: A Brief Update.International journal of molecular sciences · 2022
    Review
  13. Synthesis of FeFrontiers in bioengineering and biotechnology · 2022
    Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Yuan LuDepartment of Respiratory and Critical Care Medicine, Zhongda Hospital, Southeast University, Nanjing, Jiangsu, China.
Jing HuangDepartment of Respiratory and Critical Care Medicine, Zhongda Hospital, Southeast University, Nanjing, Jiangsu, China.
Fakai LiDepartment of Respiratory and Critical Care Medicine, Jinhua Guangfu Hospital, Jinhua, Zhejiang, China.
Yuan WangThe Second Section of Internal Medicine, Xi'an Thoracic Hospital, Xi'an, Shannxi, China.
Ming DingDepartment of Respiratory and Critical Care Medicine, Zhongda Hospital, Southeast University, Nanjing, Jiangsu, China.
Jian ZhangDepartment of Respiratory and Critical Care Medicine, Xijing Hospital, Air Force Medical University of PLA (the Fourth Military Medical University), Xi'an, China.
Hong YinDepartment of Radiology, Xijing Hospital, Air Force Medical University of PLA (the Fourth Military Medical University), Xi'an, Shannxi, China. yinhong@fmmu.edu.cn.
Rui ZhangThe State Key Laboratory of Cancer Biology, Department of Immunology, Air Force Medical University of PLA (the Fourth Military Medical University), Xi'an, Shannxi, China. ruizhang@fmmu.edu.cn.
Xinling RenDepartment of Respiratory, Shenzhen University General Hospital, Shenzhen University, Xueyuan Ave. 1098, Shenzhen, 518055, Guangdong, China. renxlmaj@126.com.
Air Force Medical University · CNZhongda Hospital Southeast University · CNGuang Fu Hospital · CNShenzhen University · CN

Funding

Basic Research Program of Jiangsu Province BK20201484Jiangsu Science and Technology Department BE2017745National Natural Science Foundation of China 81871880
6 · The paper itself

Abstract

Overexpression of epidermal growth factor receptor (EGFR) is closely associated with a poor prognosis in non-small cell lung cancer (NSCLC), thus making it a promising biomarker for NSCLC diagnosis. Here, we conjugated a single-chain antibody (scFv) targeting EGFR with Fe

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsMetal NanoparticlesSingle-Chain AntibodiesAnimalsCell Line, TumorContrast MediaErbB ReceptorsGoldMagnetic Resonance ImagingMagnetite NanoparticlesMiceContrast MediaErbB ReceptorsGoldMagnetite NanoparticlesSingle-Chain AntibodiesEGFRMRINSCLCSuperparamagnetic iron oxide nanoparticle

Identifiers

PMID33624188
PMCPMC7902179
OpenAlexW3129786569

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.