Evidence map›Paper›PMID 33624172›Full record

SynthesisJournal of cancer survivorship : research and practice2021

Cost-effectiveness of physical activity interventions in cancer survivors of developed countries: a systematic review.

Barbara E Gubler-Gut, Johannes Pöhlmann, Aline Flatz, Matthias Schwenkglenks, Sabine Rohrmann

Open access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in Journal of cancer survivorship : research and practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
1.5field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. Effects of physical exercise on body fat and laboratory biomarkers in cancer patients: a meta-analysis of 35 randomized controlled trials.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
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  6. Barriers and facilitators of physical activity in patients with oral cancer during surgical hospitalization: insights from a qualitative study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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  7. The influences of emotional factors on head and neck cancer patients' physical activity behavior in China: an application of the extended theory of planned behavior.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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  13. Willingness to pay for exercise oncology services: a mixed methods study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
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  15. Cost-utility analysis of a supervised exercise intervention for women with early-stage endometrial cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 2 countries.

Barbara E Gubler-GutInstitute of Physiotherapy, Zurich University of Applied Sciences, Katharina-Sulzer-Platz 9, 8400, Winterthur, Switzerland.
Johannes PöhlmannWinterthur Institute of Health Economics, Zurich University of Applied Sciences, Gertrudstrasse15, 8401, Winterthur, Switzerland.
Aline FlatzSwiss Cancer League, Effingerstrasse 40, 3001, Berne, Switzerland.
Matthias SchwenkglenksInstitute of Pharmaceutical Medicine, University of Basel, Klingenbergstrasse 61, 4056, Basel, Switzerland.
Sabine RohrmannEpidemiology, Biostatistics and Prevention Institute, University of Zurich, Hirschengraben 84, 8001, Zurich, Switzerland. sabine.rohrmann@uzh.ch.ORCID 0000-0002-2215-1200
Sulzer (Switzerland) · CHSwiss Cancer League · CHUniversity of Basel · CHUniversity of Zurich · CHZHAW Zurich University of Applied Sciences · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePhysical activity has been shown to improve survival and quality of life of cancer patients. Due to differences in patient populations, healthcare settings, and types of intervention, cost-effectiveness analyses of physical activity interventions in cancer survivors are difficult to compare. Available evidence from breast cancer survivor research has shown inconsistent results, and transfer of results to other types of cancer is not straightforward. This paper systematically reviewed current evidence on the cost-effectiveness of physical activity interventions in cancer survivors independent of cancer type compared to usual care or another experimental intervention.

methodsThe literature search was conducted in seven databases and enhanced by a search for gray literature. Eligible studies were restricted to developed countries and assessed using the CHEERS, CHEC, and PHILIPS checklists. The study protocol was pre-published in PROSPERO.

resultsSeven studies, five cost-utility, and two combined cost-utility/cost-effectiveness analyses fully met the inclusion criteria. They covered eight different types of cancer and various interventions. The cost-effectiveness analyses were of moderate to high methodological quality. A high probability of cost-effectiveness was reported in two analyses. One intervention appeared to be not cost-effective, and one to be cost-effective only from an organizational perspective. Three other analyses reported a cost-effectiveness better than US$ 101,195 (€ 80,000) per QALY gained.

conclusionsPhysical activity interventions in cancer survivors of developed countries were cost-effective in some but not all clinical trials reviewed. IMPLICATIONS FOR CANCER SURVIVORS: Cost-effectiveness of physical activity interventions appear to depend upon the intensity of the activity.

Indexed as

Breast NeoplasmsCancer SurvivorsCost-Benefit AnalysisDeveloped CountriesExerciseFemaleHumansQuality of LifeCancer survivorCost-effectivenessCost-utilityPhysical activity

Identifiers

PMID33624172
PMCPMC8521580
OpenAlexW3131917876

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.