Evidence map›Paper›PMID 33624119›Full record

SynthesisEuropean journal of clinical pharmacology2021

Impact of computerised physician order entry (CPOE) on the incidence of chemotherapy-related medication errors: a systematic review.

Suresh Kumar Srinivasamurthy, Ramkumar Ashokkumar, Sunitha Kodidela, Scott C Howard, Caroline Flora Samer, Uppugunduri Satyanarayana Chakradhara Rao

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in European journal of clinical pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Evaluating the Impact of Pharmacist Dual Verification of Anticancer Therapy in the Modern Era.The Journal of pharmacy technology : jPT : official publication of the Association of Pharmacy Technicians · 2023
    Article
  5. Article
  6. eHealth: A Survey of Architectures, Developments in mHealth, Security Concerns and Solutions.International journal of environmental research and public health · 2022
    Article
  7. Assessment and analysis of outpatient medication errors related to pediatric prescriptions.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2021
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Suresh Kumar SrinivasamurthyDepartment of Pharmacology, Ras Al Khaimah College of Medical Sciences, Ras Al Khaimah Medical and Health Sciences University, Ras Al Khaimah, United Arab Emirates.
Ramkumar AshokkumarCancer Services Business Informatics, Helen Diller Family Comprehensive Cancer, University of California, San Francisco (UCSF), San Francisco, CA, USA.
Sunitha KodidelaThe University of Tennessee Health Science Center, Memphis, TN, USA.
Scott C HowardDepartment of Acute and Critical Care, College of Nursing, University of Tennessee Health Science Center, Memphis, TN, USA.
Caroline Flora SamerDivision of Clinical Pharmacology and Toxicology, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Uppugunduri Satyanarayana Chakradhara RaoResearch Platform for Pediatric Onco-Hematology, Department of Paediatrics, Gynaecology and Obstetrics, University of Geneva, Geneva, Switzerland. Chakradhara.Uppugunduri@unige.ch.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeComputerised prescriber (or physician) order entry (CPOE) implementation is one of the strategies to reduce medication errors. The extent to which CPOE influences the incidence of chemotherapy-related medication errors (CMEs) was not previously collated and systematically reviewed. Hence, this study was designed to collect, collate, and systematically review studies to evaluate the effect of CPOE on the incidence of CMEs.

methodsA search was performed of four databases from 1 January 1995 until 1 August 2019. English-language studies evaluating the effect of CPOE on CMEs were selected as per inclusion and exclusion criteria. The total CMEs normalised to total prescriptions pre- and post-CPOE were extracted and collated to perform a meta-analysis using the 'meta' package in R. The systematic review was registered with PROSPERO CRD42018104220.

resultsThe database search identified 1621 studies. After screening, 19 studies were selected for full-text review, of which 11 studies fulfilled the selection criteria. The meta-analysis of eight studies with a random effects model showed a risk ratio of 0.19 (95% confidence interval: 0.08-0.44) favouring CPOE (I

conclusionThe studies have shown consistent reduction in CMEs after CPOE implementation, except one study that showed an increase in CMEs. The random effects model in the meta-analysis of eight studies showed that CPOE implementation reduced CMEs by 81%.

Indexed as

Antineoplastic AgentsConsumer BehaviorHumansMedical Order Entry SystemsMedication ErrorsPatient AcuityAntineoplastic AgentsChemotherapyCPOEMedication errorsPatient safetyPrescription

Identifiers

PMID33624119
PMCPMC8275496

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.