Evidence map›Paper›PMID 33623681›Full record

ArticleClinical kidney journal2021

The impact of volume overload on technique failure in incident peritoneal dialysis patients.

François Vrtovsnik, Christian Verger, Wim Van Biesen, Stanley Fan, Sug-Kyun Shin, Carmen Rodríguez, Isabel Garcia Méndez, Frank M van der Sande, Tatiana De Los Ríos, Katharina Ihle and 4 more

Open access · goldAbstract read
In one paragraph

Article in Clinical kidney journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.

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  14. Five Things to Know About Volume Overload in Peritoneal Dialysis.Canadian journal of kidney health and disease · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 10 institutions in 9 countries.

François VrtovsnikDepartment of Nephrology, Xavier Bichat Hospital, Paris, France.
Christian VergerRegistre de Dialyse Péritonéale de Langue Française, Pontoise, France.ORCID 0000-0002-8009-5366
Wim Van BiesenRenal Division, Ghent University Hospital, Ghent, Belgium.ORCID 0000-0002-4782-5224
Stanley FanDepartment of Renal Medicine and Transplantation, The Royal London Hospital, London, UK.
Sug-Kyun ShinDepartment of Internal Medicine, NHIC ILsan Hospital, Koyang, Korea.
Carmen RodríguezNephrology Service, Hospital Universitario Central de Asturia, Oviedo, Spain.
Isabel Garcia MéndezServicio de Nefrología, Hospital Josep Trueta, Girona, Spain.
Frank M van der SandeDepartment of Internal Medicine, University Hospital Maastricht, Maastricht, The Netherlands.
Tatiana De Los RíosClinical and Epidemiological Research, Fresenius Medical Care Deutschland GmbH, Bad Homburg, Germany.
Katharina IhleClinical and Epidemiological Research, Fresenius Medical Care Deutschland GmbH, Bad Homburg, Germany.
Adelheid GaulyClinical and Epidemiological Research, Fresenius Medical Care Deutschland GmbH, Bad Homburg, Germany.ORCID 0000-0002-2554-0711
Claudio RoncoDepartment of Nephrology Dialysis and Transplantation International Renal Research Institute (IRRIV), San Bortolo Hospital, Vicenza, Italy.
James HeafDepartment of Medicine, Zealand University Hospital, Roskilde, Denmark.
IPOD-PD Study Group
Fresenius Medical Care (Germany) · DEGhent University Hospital · BEHôpital Xavier Arnozan · FRHospital Universitari de Girona Doctor Josep Trueta · ESHospital Universitario Central de Asturias · ESInternational Renal Research Institute of Vicenza · ITMaastricht University Medical Centre · NLNational Health Insurance Service Ilsan Hospital · KRRoyal London Hospital · GBZealand University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTechnique failure in peritoneal dialysis (PD) can be due to patient- and procedure-related factors. With this analysis, we investigated the association of volume overload at the start and during the early phase of PD and technique failure.

methodsIn this observational, international cohort study with longitudinal follow-up of incident PD patients, technique failure was defined as either transfer to haemodialysis or death, and transplantation was considered as a competing risk. We explored parameters at baseline or within the first 6 months and the association with technique failure between 6 and 18 months, using a competing risk model.

resultsOut of 1092 patients of the complete cohort, 719 met specific inclusion and exclusion criteria for this analysis. Being volume overloaded, either at baseline or Month 6, or at both time points, was associated with an increased risk of technique failure compared with the patient group that was euvolaemic at both time points. Undergoing treatment at a centre with a high proportion of PD patients was associated with a lower risk of technique failure.

conclusionsVolume overload at start of PD and/or at 6 months was associated with a higher risk of technique failure in the subsequent year. The risk was modified by centre characteristics, which varied among regions.

Indexed as

bioimpedancecohort studyfluid overloadperitoneal dialysistechnique failure

Identifiers

PMID33623681
PMCPMC7886558
OpenAlexW2997240357

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.