Evidence map›Paper›PMID 33623676›Full record

ArticleClinical kidney journal2021

Anti-Müllerian hormone concentrations in women with chronic kidney disease.

Kate Wiles, Ellen Anckaert, Francesca Holden, Jan Grace, Catherine Nelson-Piercy, Liz Lightstone, Lucy C Chappell, Kate Bramham

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Clinical kidney journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Impact of CKD on Female Reproductive Hormones.Kidney international reports · 2025
    Article
  4. Kidney disease and reproductive health.Nature reviews. Nephrology · 2025
    Review
  5. Female Infertility in Chronic Kidney Disease.Diagnostics (Basel, Switzerland) · 2023
    Review
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Kate WilesDepartment of Women and Children's Health, King's College London, London, UK.ORCID 0000-0003-0617-8144
Ellen AnckaertLaboratory of Hormonology and Tumour Markers, Universitair Ziekenhuis Brussel, Free University of Brussels, Brussels, Belgium.
Francesca HoldenDepartment of Renal Medicine, King's College Hospital NHS Foundation Trust, London, UK.
Jan GraceGuy's and St Thomas NHS Foundation Trust, London, UK.
Catherine Nelson-PiercyGuy's and St Thomas NHS Foundation Trust, London, UK.
Liz LightstoneImperial Healthcare NHS Trust, London, UK.
Lucy C ChappellDepartment of Women and Children's Health, King's College London, London, UK.
Kate BramhamDepartment of Women and Children's Health, King's College London, London, UK.
King's College London · GBImperial College Healthcare NHS Trust · GBGuy's and St Thomas' NHS Foundation Trust · GBKing's College Hospital NHS Foundation Trust · GBUniversitair Ziekenhuis Brussel · BE

Funding

Department of Health RP-2014-05-019
6 · The paper itself

Abstract

backgroundSerum anti-Müllerian hormone (AMH) is a biomarker of ovarian reserve. There are limited data to guide the clinical interpretation of AMH in women with chronic kidney disease (CKD). The purpose of this study was to examine AMH concentrations in women with CKD compared with women without CKD.

methodsWe conducted a prospective cohort study of serum AMH concentrations in 163 non-pregnant women with CKD. Serum AMH concentrations were compared with age-specific AMH centiles from 887 healthy female controls.

resultsParticipants included 30 women with Stage 1 CKD, 37 women with Stage 2 CKD, 26 women with Stage 3a CKD, 31 women with Stage 3b CKD and 39 women with Stages 4 and 5 CKD. The median estimated glomerular filtration rate (eGFR) was 51 (interquartile range 31-80) mL/min/1.73 m

conclusionsWomen with CKD have a lower ovarian reserve and are predicted to have a lower ovarian response to gonadotrophin stimulation compared with women without CKD of a similar age. Women with CKD who fail to conceive within 6 months of regular unprotected intercourse should be considered for fertility assessment and intervention.

Indexed as

anti-Müllerian hormonefertilityinfertilityrenal insufficiency

Identifiers

PMID33623676
PMCPMC7886554
OpenAlexW4250662967

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.