Evidence map›Paper›PMID 33623535›Full record

ArticleApplied bionics and biomechanics2021

Diagnosis of Alzheimer Disease Using 2D MRI Slices by Convolutional Neural Network.

Fanar E K Al-Khuzaie, Oguz Bayat, Adil D Duru

RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in Applied bionics and biomechanics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 88 citations in OpenAlex.

  1. Pooled it
  2. Insertion Network for Image Sequence Correspondence Building.Proceedings of SPIE--the International Society for Optical Engineering · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Fanar E K Al-KhuzaieGraduate School of Science and Engineering, Altinbas University, Istanbul, Turkey.ORCID https://orcid.org/0000-0001-5632-6569
Oguz BayatGraduate School of Science and Engineering, Altinbas University, Istanbul, Turkey.ORCID https://orcid.org/0000-0001-5988-8882
Adil D DuruDepartment of Physical Education and Sports Teaching, University of Marmara, Istanbul, Turkey.ORCID https://orcid.org/0000-0003-3014-9626
Altınbaş University · TRMarmara University · TR

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Smartphone-Based "Burst" Cognitive AssessmentsP01AG003991 · NIA · WASHINGTON UNIVERSITY · PI JOHN MORRIS · 1985 to 2026
$69.5M
The natural history of AB accumulation in preclinical ADP01AG026276 · NIA · WASHINGTON UNIVERSITY · PI MORRIS, JOHN · 2005 to 2025
$49.5M
Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
THE XNAT IMAGING INFORMATICS PLATFORMR01EB009352 · NIBIB · WASHINGTON UNIVERSITY · PI Daniel Scott Marcus · 2009 to 2026
$9.3M
DRIVING PERFORMANCE IN PRECLINICAL ALZHEIMER'S DISEASER01AG043434 · NIA · WASHINGTON UNIVERSITY · PI ROE, CATHERINE M · 2012 to 2016
$2.4M
NCATS NIH HHS UL1 TR000448NCATS NIH HHS UL1 TR002345NIA NIH HHS P01 AG003991NIA NIH HHS P01 AG026276NIA NIH HHS R01 AG043434NIBIB NIH HHS R01 EB009352
6 · The paper itself

Abstract

There are many kinds of brain abnormalities that cause changes in different parts of the brain. Alzheimer's disease is a chronic condition that degenerates the cells of the brain leading to memory asthenia. Cognitive mental troubles such as forgetfulness and confusion are one of the most important features of Alzheimer's patients. In the literature, several image processing techniques, as well as machine learning strategies, were introduced for the diagnosis of the disease. This study is aimed at recognizing the presence of Alzheimer's disease based on the magnetic resonance imaging of the brain. We adopted a deep learning methodology for the discrimination between Alzheimer's patients and healthy patients from 2D anatomical slices collected using magnetic resonance imaging. Most of the previous researches were based on the implementation of a 3D convolutional neural network, whereas we incorporated the usage of 2D slices as input to the convolutional neural network. The data set of this research was obtained from the OASIS website. We trained the convolutional neural network structure using the 2D slices to exhibit the deep network weightings that we named as the Alzheimer Network (AlzNet). The accuracy of our enhanced network was 99.30%. This work investigated the effects of many parameters on AlzNet, such as the number of layers, number of filters, and dropout rate. The results were interesting after using many performance metrics for evaluating the proposed AlzNet.

Identifiers

PMID33623535
PMCPMC7872776
OpenAlexW3126870425

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.