Evidence map›Paper›PMID 33623379›Full record

ArticleInternational journal of chronic obstructive pulmonary disease

Standardisation of Clinical Assessment, Management and Follow-Up of Acute Hospitalised Exacerbation of COPD: A Europe-Wide Consensus.

Sanjay Ramakrishnan, Wim Janssens, Pierre-Regis Burgel, Marco Contoli, Frits M E Franssen, Neil J Greening, Timm Greulich, Iwein Gyselinck, Andreas Halner, Arturo Huerta and 6 more

Open access · goldAbstract readConsensus Statement
In one paragraph

Article in International journal of chronic obstructive pulmonary disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 27 citations in OpenAlex.

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  4. Optimizing COPD Care in Belgium: A Multidisciplinary Expert Consensus on Cardiopulmonary Risk Management.International journal of chronic obstructive pulmonary disease · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 13 institutions in 10 countries.

Sanjay RamakrishnanRespiratory Medicine Unit, Nuffield Department of Medicine - Experimental Medicine, University of Oxford, Oxford, UK.ORCID 0000-0002-3003-7918
Wim JanssensDepartment of Respiratory Diseases, UZ Leuven, Research Group BREATHE, KU Leuven, Leuven, Belgium.ORCID 0000-0003-1830-2982
Pierre-Regis BurgelFaculty of Medicine, University of Paris and INSERM 1016 Institut Cochin, Cochin Hospital, Assistance Publique Hôpitaux de Paris, Paris, France.ORCID 0000-0003-0903-9828
Marco ContoliDepartment of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy.ORCID 0000-0002-2731-5809
Frits M E FranssenDepartment of Respiratory Medicine, Maastricht University Medical Center, Maastricht, Netherlands.ORCID 0000-0002-1633-6356
Neil J GreeningDepartment of Respiratory Sciences, NIHR Leicester Biomedical Research Centre (Respiratory), Glenfield Hospital, Leicester, UK.
Timm GreulichDepartment of Medicine, Pulmonary and Critical Care Medicine, University Medical Centre Giessen and Marburg, Philipps University, Member of the German Centre for Lung Research (DZL), Marburg, Germany.
Iwein GyselinckDepartment of Respiratory Diseases, UZ Leuven, Research Group BREATHE, KU Leuven, Leuven, Belgium.
Andreas HalnerRespiratory Medicine Unit, Nuffield Department of Medicine - Experimental Medicine, University of Oxford, Oxford, UK.
Arturo HuertaPulmonary and Critical Care Division, Clinica Sagrada Familia, IDIBAPS August Pi i Sunyer Biomedical Research Institute, Barcelona, Spain.ORCID 0000-0002-6191-4143
Rebecca L MorganDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Canada.ORCID 0000-0002-1012-4897
Jennifer K QuintNational Heart & Lung Institute, Imperial College, London, UK.ORCID 0000-0003-0149-4869
Lowie E G W VanfleterenCOPD Center, Department of Respiratory Medicine and Allergology, Sahlgrenska University Hospital, Department of Internal Medicine and Clinical Nutrition at Institute of Medicine, SU Sahlgrenska, Göteborg, Sweden.
Kristina VermeerschDepartment of Respiratory Diseases, UZ Leuven, Research Group BREATHE, KU Leuven, Leuven, Belgium.
Henrik WatzPulmonary Research Institute at LungenClinic Grosshansdorf, Airway Research Center North (ARCN), German Center for Lung Research (DZL), Grosshansdorf, Germany.
Mona BafadhelRespiratory Medicine Unit, Nuffield Department of Medicine - Experimental Medicine, University of Oxford, Oxford, UK.ORCID 0000-0002-9993-2478
Universitair Ziekenhuis Leuven · BEUniversity of Oxford · GBConsorci Institut D'Investigacions Biomediques August Pi I Sunyer · ESEdith Cowan University · AUGerman Center for Lung Research · DEGlenfield Hospital · GBImpact · CAImperial College London · GBInserm · FRMaastricht University · NLSahlgrenska University Hospital · SEUniversities of Giessen and Marburg Lung Center · DEUniversity of Ferrara · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite hospitalization for exacerbation being a high-risk event for morbidity and mortality, there is little consensus globally regarding the assessment and management of hospitalised exacerbations of COPD. We aimed to establish a consensus list of symptoms, physiological measures, clinical scores, patient questionnaires and investigations to be obtained at time of hospitalised COPD exacerbation and follow-up.

methodsA modified Delphi online survey with pre-defined consensus of importance, feasibility and frequency of measures at hospitalisation and follow-up of a COPD exacerbation was undertaken.

findingsA total of 25 COPD experts from 18 countries contributed to all 3 rounds of the survey. Experts agreed that a detailed history and examination were needed. Experts also agreed on which treatments are needed and how soon these should be delivered. Experts recommended that a full blood count, renal function, C-reactive protein and cardiac blood biomarkers (BNP and troponin) should be measured within 4 hours of admission and that the modified Medical Research Council dyspnoea scale (mMRC) and COPD assessment test (CAT) should be performed at time of exacerbation and follow-up. Experts encouraged COPD clinicians to strongly consider discussing palliative care, if indicated, at time of hospitalisation.

interpretationThis Europe-wide consensus document is the first attempt to standardise the assessment and care of patients hospitalised for COPD exacerbations. This should be regarded as the starting point to build knowledge and evidence on patients hospitalised for COPD exacerbations.

Indexed as

Pulmonary Disease, Chronic ObstructiveDisease ProgressionEuropeFollow-Up StudiesHumansconsensus developmentCOPDdisease exacerbationexpert opinionhospitalisationpatient care

Identifiers

PMID33623379
PMCPMC7896731
OpenAlexW3132624541

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.