ArticleScientific reports2021
Predictors for blood loss and transfusion frequency to guide blood saving programs in primary knee- and hip-arthroplasty.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Suction drain usage has no benefit following revision total hip and knee arthroplasty.Archives of orthopaedic and trauma surgery · 2024Pooled it
- Chronic Corticosteroid Use Is Associated with Higher Perioperative Morbidity After Elective Primary Total Hip Arthroplasty.Journal of clinical medicine · 2026Article
- Low-dose erythropoietin in anemic arthroplasty patients within contemporary patient blood management pathways.Journal of orthopaedic surgery and research · 2026Article
- Perioperative Factors Associated With Allogeneic Blood Transfusion in Elective THA.Orthopaedic surgery · 2026Article
- Impact of Anemia on Outcomes Following Total Hip Replacement Surgery and Patient Prognosis.Orthopaedic surgery · 2026Review
- Article
- Preoperative Coagulation Markers and Clinical Predictors of Transfusion Requirement in Patients Undergoing Total Knee or Hip Arthroplasty: A Single-Center Retrospective Study.Medical sciences (Basel, Switzerland) · 2025Article
- Blood transfusion in total knee arthroplasty and total hip arthroplasty: A nationwide study of complications, costs and predictive modelling.Journal of experimental orthopaedics · 2025Article
- Article
- Enhancing bleeding control in total knee arthroplasty for osteoarthritis and rheumatic diseases: strategies and insights.Reumatologia · 2025Review
- Development and Validation of a Machine Learning Algorithm to Predict the Risk of Blood Transfusion after Total Hip Replacement in Patients with Femoral Neck Fractures: A Multicenter Retrospective Cohort Study.Orthopaedic surgery · 2024Article
- Nano fuzzy alarming system for blood transfusion requirement detection in cancer using deep learning.Scientific reports · 2024Article
- Article
- A neck-sparing short stem shows significantly lower blood loss in total hip arthroplasty compared to a neck-resecting short stem.Scientific reports · 2023Article
- Predictive and protective factors for allogenic blood transfusion in total knee arthroplasty. A retrospective cohort study.Journal of orthopaedics · 2023Article
- Artificial neural networks for the prediction of transfusion rates in primary total hip arthroplasty.Archives of orthopaedic and trauma surgery · 2023Article
- Prevalence of modifiable risk factors in primary elective arthroplasty and their association with infections.Acta orthopaedica · 2023Article
- Personalized Surgical Transfusion Risk Prediction Using Machine Learning to Guide Preoperative Type and Screen Orders.Anesthesiology · 2022Article
- Perioperative Blood Loss Can Be Reduced If Total Knee Arthroplasty Was Performed in the Si Hour-Period, Compared with the Wei Hour-Period: A Retrospective Cohort Study.Evidence-based complementary and alternative medicine : eCAM · 2021Article
- The probability of allogeneic blood transfusion and its influencing factors in patients undergoing total knee arthroplasty: A retrospective cohort study.Asian journal of transfusion scienceArticle
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Endoprosthetic surgery can lead to relevant blood loss resulting in red blood cell (RBC) transfusions. This study aimed to identify risk factors for blood loss and RBC transfusion that enable the prediction of an individualized transfusion probability to guide preoperative RBC provision and blood saving programs. A retrospective analysis of patients who underwent primary hip or knee arthroplasty was performed. Risk factors for blood loss and transfusions were identified and transfusion probabilities computed. The number needed to treat (NNT) of a potential correction of preoperative anemia with iron substitution for the prevention of RBC transfusion was calculated. A total of 308 patients were included, of whom 12 (3.9%) received RBC transfusions. Factors influencing the maximum hemoglobin drop were the use of drain, tranexamic acid, duration of surgery, anticoagulation, BMI, ASA status and mechanical heart valves. In multivariate analysis, the use of a drain, low preoperative Hb and mechanical heart valves were predictors for RBC transfusions. The transfusion probability of patients with a hemoglobin of 9.0-10.0 g/dL, 10.0-11.0 g/dL, 11.0-12.0 g/dL and 12.0-13.0 g/dL was 100%, 33.3%, 10% and 5.6%, and the NNT 1.5, 4.3, 22.7 and 17.3, while it was 100%, 50%, 25% and 14.3% with a NNT of 2.0, 4.0, 9.3 and 7.0 in patients with a drain, respectively. Preoperative anemia and the insertion of drains are more predictive for RBC transfusions than the use of tranexamic acid. Based on this, a personalized transfusion probability can be computed, that may help to identify patients who could benefit from blood saving programs.
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