Evidence map›Paper›PMID 33622997›Full record

Trial reportCurrent oncology (Toronto, Ont.)2020

Efficacy of

Golmehr Sistani, Duncan E K Sutherland, Amol Mujoomdar, Daniele P Wiseman, Alireza Khatami, Elena Tsvetkova, Robert H Reid, David T Laidley

Abstract readClinical Trial, Phase II
In one paragraph

Trial report in Current oncology (Toronto, Ont.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Survival predictors ofJournal of cancer research and clinical oncology · 2022
    Trial
  3. Review
  4. Safety and efficacy of re-treatment with [European journal of nuclear medicine and molecular imaging · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Use of imaging-based dosimetry for personalising radiopharmaceutical therapy of cancer.Cancer imaging : the official publication of the International Cancer Imaging Society · 2022
    Review
  12. Review
  13. Understanding the Radiobiological Mechanisms Induced byInternational journal of molecular sciences · 2022
    Article
  14. Review
  15. Review
  16. Toxicity and Tolerability ofCurrent radiopharmaceuticals · 2022
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Golmehr SistaniDepartment of Nuclear Medicine, Department of Medical Imaging, Western University, London, ON N6A 3K7, Canada.ORCID 0000-0002-6525-5157
Duncan E K SutherlandDepartment of Nuclear Medicine, Department of Medical Imaging, Western University, London, ON N6A 3K7, Canada.
Amol MujoomdarDepartment of Radiology, Department of Medical Imaging, Western University, London, ON N6A 3K7, Canada.
Daniele P WisemanDepartment of Radiology, Department of Medical Imaging, Western University, London, ON N6A 3K7, Canada.
Alireza KhatamiDepartment of Nuclear Medicine, Department of Medical Imaging, Western University, London, ON N6A 3K7, Canada.ORCID 0000-0002-6320-7565
Elena TsvetkovaDepartment of Medical Oncology, Western University, London, ON N6A 3K7, Canada.
Robert H ReidDepartment of Nuclear Medicine, Department of Medical Imaging, Western University, London, ON N6A 3K7, Canada.
David T LaidleyDepartment of Nuclear Medicine, Department of Medical Imaging, Western University, London, ON N6A 3K7, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peptide receptor radionuclide therapy (PRRT) has been recently established as a treatment option for progressive gastro-entero-pancreatic neuroendocrine tumors (NETs) including four 200 mCi induction cycles. The purpose of this phase 2 trial is to expand use of PRRT to different types of NETs with the application of dose adjustment and evaluate value of maintenance therapy in patients who had disease control on induction therapy. Forty-seven PRRT naïve NET patients with different primary origin received

Indexed as

Neuroendocrine TumorsHumansProgression-Free SurvivalRadiopharmaceuticalsRegistriesRadiopharmaceuticalsDOTATAELu-177NETneuroendocrine tumorpeptide receptor radionuclide therapyPRRT

Identifiers

PMID33622997
PMCPMC7816182

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.