Evidence map›Paper›PMID 33622917›Full record

ArticleIn vivo (Athens, Greece)

Outcome of Radiation Therapy for Stage IVB Uterine Cervical Cancer With Distant Lymph Nodes Metastases; Sequential Irradiation for Distant Lymph Nodes Metastases.

Yuki Mukai, Naho Ruiz Yokota, Madoka Sugiura, Taichi Mizushima, Risa Taniuchi, Yuichi Imai, Kotaro Hashimoto, Yuya Tabuchi, Etusko Miyagi, Masaharu Hata

Open access · diamondAbstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Review
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  4. Article
  5. Outcomes associated with treatment to all sites of disease in patients with stage IVB cancer of the cervix.International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Yuki MukaiDepartment of Radiation Oncology, Yokohama City University Graduate School of Medicine, Yokohama, Japan; y_mukai@yokohama-cu.ac.jp.
Naho Ruiz YokotaDepartment of Obstetrics and Gynecology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Madoka SugiuraDepartment of Radiation Oncology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Taichi MizushimaDepartment of Obstetrics and Gynecology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Risa TaniuchiDepartment of Radiation Oncology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Yuichi ImaiDepartment of Obstetrics and Gynecology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Kotaro HashimotoDepartment of Radiation Oncology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Yuya TabuchiDepartment of Radiation Oncology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Etusko MiyagiDepartment of Obstetrics and Gynecology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Masaharu HataDepartment of Radiation Oncology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Yokohama City University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimThis study aimed to evaluate the outcome of radiation therapy for patients with distant lymph node (LN) metastases, without organ metastases from uterine cervical cancer (UCC). PATIENTS AND

methodsTwenty-six patients with UCC with distant LN metastases received radiotherapy and were retrospectively analyzed. The sites of distant LN metastasis were as follows; Supraclavicular in 19, inguinal in nine, axillary in four, and others in three. The mean dose prescribed for these was 50 (range=40-60) Gy.

resultsThe 2-year overall, cause-specific, and progression-free survival, and local control of primary tumor rates were 51.3%, 51.3%, 46.9%, and 67.9%. In multivariate analysis, performance status ≥1 (p=0.007), para-aortic LN metastases (p=0.001), and lack of high-dose-rate intracavitary brachytherapy (p=0.033) were significantly associated with poor overall survival. Performance status ≥1 (p=0.004), and para-aortic LN metastases (p=0.014) were significantly associated with poor cause-specific survival.

conclusionThis study demonstrated favorable local control in patients with UCC with distant LN metastases.

Indexed as

Uterine Cervical NeoplasmsFemaleHumansLymphatic MetastasisLymph NodesNeoplasm StagingRetrospective Studiesdistant lymph node metastasesexternal beam radiation therapysupraclavicular lymph node metastasesthree-dimensional radiation therapyUterine cervical cancer

Identifiers

PMID33622917
PMCPMC8045121
OpenAlexW3130633962

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.