SynthesisIn vivo (Athens, Greece)
Pelvic Insufficiency Fractures in Cervical Cancer After Radiation Therapy: A Meta-Analysis and Review.
Synthesis in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Pelvic insufficiency fractures after radiation therapy for pelvic cancer in female patients: an updated meta-analysis of 11,272 patients.Archives of orthopaedic and trauma surgery · 2026Pooled it
- Prevention and management of radiotherapy-related toxicities in gynecological malignancies. Position paper on behalf of AIRO (Italian Association of Radiotherapy and Clinical Oncology).La Radiologia medica · 2024Guideline
- Clinical and 18F-FDG PET/CT Imaging Characteristics of Post-radiotherapy Sacral Insufficiency Fractures in Cervical Cancer Patients.Current medical imaging · 2026Article
- Risk of Pelvic Insufficiency Fractures in Cervical Cancer Survivors: Using the National Claim Database.Journal of Korean medical science · 2025Article
- Detection of vertebral insufficiency fractures onRadiology case reports · 2025Article
- Risk of fragility fracture of pelvis in endometrial cancer survivors : A national claim database study.Archives of osteoporosis · 2025Article
- Insufficiency fractures in patients with sacral chordoma treated with high-dose radiation therapy with and without resection.BJR open · 2025Article
- Insights into pelvic insufficiency fracture following pelvic radiotherapy for cervical cancer: a comparative review.BMC women's health · 2024Review
- Radiation-Related Fractures after Radical Radiotherapy for Cervical and Endometrial Cancers: Are There Any Differences?Diagnostics (Basel, Switzerland) · 2024Article
- Musculoskeletal Pitfalls on Molecular Imaging Studies of Oncologic Patients: How to Stay Out of Trouble.Tomography (Ann Arbor, Mich.) · 2024Review
- Pelvic insufficiency fractures after intensity modulated radiation therapy combined with chemotherapy for cervix carcinoma: Incidence and impact of bone mineral density.Clinical and translational radiation oncology · 2023Article
- Superiority of MRI for Evaluation of Sacral Insufficiency Fracture.Journal of clinical medicine · 2022Article
- Symptom burden and health-related quality of life six months after hyperbaric oxygen therapy in cancer survivors with pelvic radiation injuries.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Article
- Therapy-induced bone changes in oncology imaging withAnnals of nuclear medicine · 2022Review
- PET/MRI is useful for early detection of pelvic insufficiency fractures after radiotherapy for cervical cancer.Oncology letters · 2021Article
- Relations Between Bone Quantity, Microarchitecture, and Collagen Cross-links on Mechanics Following In Vivo Irradiation in Mice.JBMR plus · 2021Article
- Pelvic Insufficiency Fractures and Bone Pain after Radiation Therapy for Anal Cancer: Relation to Pelvic Bone Dose-Volume Parameters.Advances in radiation oncologyArticle
- Pretreatment computed tomography L1 attenuation values: Easy reaching predicting factor for radiation-related bone insufficiency fractures in females treated for advanced cervical cancer (prospective study).Women's health (London, England)Article
- Risk Factors for Sacral Insufficiency Fracture After Pelvic Irradiation for Cervical Cancer.In vivo (Athens, Greece)Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimThe aim of the study was to estimate the prevalence of pelvic insufficiency fractures (PIFs) after radiation therapy (RT) in patients with cervical cancer. PATIENTS AND
methodsA total of 3,633 patients from 15 cohort studies were included. Proportion meta-analysis was performed to estimate prevalence and subgroup analysis was performed according to imaging modalities for diagnosis of PIF. For continuous variables (age and length of follow-up), meta-regression analysis was performed.
resultsPooled prevalence estimate of PIF was 14% (95% CI=10-19). Incidence of PIF was higher in studies that used MRI as a diagnostic tool (17%, 95% CI=12-22) than non-MRI (8%, 95% CI=2-14). In meta-regression, we found a significant association of prevalence of PIF with age (p=0.021) but not with length of follow-up (p=0.118).
conclusionPIF after RT in patients with cervical cancer is not rare. Physicians need to pay attention to PIFs, especially in patients with high-risk factors for osteoporotic fracture.
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