Evidence map›Paper›PMID 33622860›Full record

ReviewIn vivo (Athens, Greece)

Osteochondromas: An Updated Review of Epidemiology, Pathogenesis, Clinical Presentation, Radiological Features and Treatment Options.

Kostas Tepelenis, Georgios Papathanakos, Aikaterini Kitsouli, Theodoros Troupis, Alexandra Barbouti, Konstantinos Vlachos, Panagiotis Kanavaros, Panagiotis Kitsoulis

Open access · diamondAbstract readReview
In one paragraph

Review in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 102 papers.

0numbers the graph read from it
0cells of the map it votes in
102citing papers in PubMed
24.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

102 citing papers in PubMed, 212 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Intraosseous tumours of the knee.Skeletal radiology · 2026
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Endoscopic Osteochondroma Resection for Treatment of Ischiofemoral Impingement Through Posterior Approach: A Case Report.Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine · 2026
    Article
  10. Review
  11. Association of Cartilage Cap Thickness With Tumor Grade and Outcomes in Secondary Chondrosarcoma.The Journal of the American Academy of Orthopaedic Surgeons · 2026
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article

42 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Kostas TepelenisDepartment of Surgery, University Hospital of Ioannina, Ioannina, Greece; kostastepelenis@gmail.com.
Georgios PapathanakosIntensive Care Unit, University Hospital of Ioannina, Ioannina, Greece.
Aikaterini KitsouliAnatomy - Histology - Embryology, University of Ioannina, Ioannina, Greece.
Theodoros TroupisDepartment of Anatomy, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Alexandra BarboutiAnatomy - Histology - Embryology, University of Ioannina, Ioannina, Greece.
Konstantinos VlachosDepartment of Surgery, University Hospital of Ioannina, Ioannina, Greece.
Panagiotis KanavarosAnatomy - Histology - Embryology, University of Ioannina, Ioannina, Greece.
Panagiotis KitsoulisAnatomy - Histology - Embryology, University of Ioannina, Ioannina, Greece.
University of Ioannina · GRUniversity Hospital of Ioannina · GRNational and Kapodistrian University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteochondroma, the most common benign bone tumor, is a projection on the external surface of the bone, which can be sessile or pedunculated. 85% of osteochondromas present as solitary lesions, while 15% occur in the context of hereditary multiple exostoses (HME), a genetic disorder that is inherited in an autosomal dominant manner. Although often asymptomatic, symptoms may eventuate from compression of adjacent vessels or nerves, fractures, osseous deformities, bursa formation, or malignant transformation. Cartilage cap thickness >2 cm in adults or >3 cm in children as well as new onset of pain or growth, or rapid growth of the lesion, especially after the closure of the growth plate, might reflect cancerous transformation. Surgical resection is indicated for symptomatic lesions, complications, cosmetic reasons or malignant transformation. Excision of the tumor with free margin is the treatment of choice. Local recurrence is less than 2% if complete resection is achieved.

Indexed as

Bone NeoplasmsExostoses, Multiple HereditaryOsteochondromaAdultChildHumansNeoplasm Recurrence, LocalRadiographychondrosarcomaexostosisHMEimagingOsteochondromareview

Identifiers

PMID33622860
PMCPMC8045119
OpenAlexW3130401030

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.