Evidence map›Paper›PMID 33622793›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

A tandem activity-based sensing and labeling strategy enables imaging of transcellular hydrogen peroxide signaling.

Hidefumi Iwashita, Erika Castillo, Marco S Messina, Raymond A Swanson, Christopher J Chang

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
8.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 101 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. HJournal of medicinal chemistry · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. MdABCI17 acts as a positive regulator to enhance apple resistance toMolecular breeding : new strategies in plant improvement · 2024
    Article
  13. Article
  14. Article
  15. Review
  16. A tandem activity-based sensing and labeling strategy reveals antioxidant response element regulation of labile iron pools.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  17. Article
  18. Article
  19. Article
  20. Unveiling the Crucial Roles of OJournal of the American Chemical Society · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Hidefumi IwashitaDepartment of Chemistry, University of California, Berkeley, CA 94720.ORCID 0000-0001-6709-0897
Erika CastilloDepartment of Neurology, University of California, San Francisco and San Francisco Veterans Affairs Medical Center, San Francisco, CA 94143.ORCID 0000-0003-2492-901X
Marco S MessinaDepartment of Chemistry, University of California, Berkeley, CA 94720.ORCID 0000-0003-2827-118X
Raymond A SwansonDepartment of Neurology, University of California, San Francisco and San Francisco Veterans Affairs Medical Center, San Francisco, CA 94143.ORCID 0000-0002-3664-5359
Christopher J ChangDepartment of Chemistry, University of California, Berkeley, CA 94720; chrischang@berkeley.edu.ORCID 0000-0001-5732-9497
University of California, Berkeley · USSan Francisco VA Medical Center · US

Funding

Training CoreP42ES004705 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI MORELLO-FROSCH, RACHEL ADELE · 1987 to 2025
$74.6M
Chemical Probes to Study Formaldehyde BiologyR01ES028096 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI Christopher J. Chang · 2017 to 2026
$4.1M
Chemical Probes to Study Methionine Redox BiologyR01GM139245 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI Christopher J. Chang · 2020 to 2026
$2.9M
Ischemia-induced injury to neuronal processes: role of cofilin-actin rod formationI01BX004884 · VA · VETERANS AFFAIRS MED CTR SAN FRANCISCO · PI SWANSON, RAYMOND A · 2020 to 2023
–
BLRD VA I01 BX004884NIEHS NIH HHS P42 ES004705NIEHS NIH HHS R01 ES028096NIGMS NIH HHS R01 GM139245
6 · The paper itself

Abstract

Reactive oxygen species (ROS) like hydrogen peroxide (H

Indexed as

AnimalsBoronic AcidsCell CommunicationCerebral CortexCoculture TechniquesEmbryo, MammalianFluorescent DyesHeLa CellsHumansHydrogen PeroxideMiceMicrogliaMolecular ProbesNeuronsOxidation-ReductionParaquatBoronic AcidsFluorescent DyesHydrogen PeroxideMolecular ProbesParaquatactivity-based sensingfluorescent hydrogen peroxide probeNADPH oxidaseoxidative stressredox signaling

Identifiers

PMID33622793
PMCPMC7936376
OpenAlexW3132899487

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.