Evidence map›Paper›PMID 33622772›Full record

ArticleJournal of cell science2021

SEC24A facilitates colocalization and Ca

Tamutenda Chidawanyika, Rajarshi Chakrabarti, Kathryn S Beauchemin, Henry N Higgs, Surachai Supattapone

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cell science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. TRPM8 Regulates Mitochondrial CaJournal of cellular and molecular medicine · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Tamutenda ChidawanyikaDepartment of Biochemistry and Cell Biology, Guarini School of Graduate and Advanced Studies, Hanover, NH 03755, USA.
Rajarshi ChakrabartiDepartment of Biochemistry and Cell Biology, Guarini School of Graduate and Advanced Studies, Hanover, NH 03755, USA.
Kathryn S BeaucheminDepartment of Biochemistry and Cell Biology, Guarini School of Graduate and Advanced Studies, Hanover, NH 03755, USA.
Henry N HiggsDepartment of Biochemistry and Cell Biology, Guarini School of Graduate and Advanced Studies, Hanover, NH 03755, USA.
Surachai SupattaponeDepartment of Biochemistry and Cell Biology, Guarini School of Graduate and Advanced Studies, Hanover, NH 03755, USA supattapone@dartmouth.edu.ORCID 0000-0001-9060-4550
Dartmouth College · US

Funding

Understanding the role of RNA-binding protein mutations in cancerP20GM113132 · NIGMS · DARTMOUTH COLLEGE · PI MADDEN, DEAN R · 2016 to 2025
$25.9M
The impact of dynamic actin polymerization on mitochondrial dynamics and functionR35GM122545 · NIGMS · DARTMOUTH COLLEGE · PI HENRY N HIGGS · 2017 to 2026
$7.7M
Structural Mechanism of Mammalian Prion InfectivityR01NS118796 · NINDS · DARTMOUTH COLLEGE · PI SUPATTAPONE, SURACHAI, ZILM, KURT WILLIAM · 2020 to 2024
$2.8M
Novel Therapeutic Strategies Targeting Malleability of Wild-Type and Mutant PrionsR01NS117276 · NINDS · DARTMOUTH COLLEGE · PI SUPATTAPONE, SURACHAI · 2020 to 2025
$2.4M
Dissecting the Mechanism of Prion Formation with a Permissive HostR01NS102301 · NINDS · DARTMOUTH COLLEGE · PI SUPATTAPONE, SURACHAI · 2018 to 2021
$2.2M
NIGMS NIH HHS P20 GM113132NIGMS NIH HHS R35 GM122545NINDS NIH HHS R01 NS102301NINDS NIH HHS R01 NS117276NINDS NIH HHS R01 NS118796
6 · The paper itself

Abstract

A genome-wide screen recently identified SEC24A as a novel mediator of thapsigargin-induced cell death in HAP1 cells. Here, we determined the cellular mechanism and specificity of SEC24A-mediated cytotoxicity. Measurement of Ca

Indexed as

CalciumEndoplasmic ReticulumApoptosisMitochondriaSarcoplasmic Reticulum Calcium-Transporting ATPasesThapsigarginCalciumSarcoplasmic Reticulum Calcium-Transporting ATPasesThapsigarginApoptosisAutophagyCalciumER stressMitochondrial-associated membranesSEC24ASERCAThapsigargin

Identifiers

PMID33622772
PMCPMC8015215
OpenAlexW3129836529

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.