Evidence map›Paper›PMID 33622726›Full record

ArticlemBio2021

Cryoelectron Microscopy Structures of AdeB Illuminate Mechanisms of Simultaneous Binding and Exporting of Substrates.

Christopher E Morgan, Przemyslaw Glaza, Inga V Leus, Anhthu Trinh, Chih-Chia Su, Meng Cui, Helen I Zgurskaya, Edward W Yu

Open access · goldAbstract read
In one paragraph

Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 62 citations in OpenAlex.

  1. Article
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  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Cloning and Characterizing Multidrug Efflux Pumps.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  11. Article
  12. Article
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  15. Article
  16. Review
  17. Structural analysis of resistance-nodulation cell division transporters.Microbiology and molecular biology reviews : MMBR · 2024
    Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Christopher E Morgan *Department of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Przemyslaw Glaza *Department of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Inga V LeusDepartment of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma, USA.
Anhthu TrinhDepartment of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma, USA.
Chih-Chia SuDepartment of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Meng CuiDepartment of Pharmaceutical Sciences, Northeastern University School of Pharmacy, Boston, Massachusetts, USA.
Helen I ZgurskayaDepartment of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma, USA.
Edward W YuDepartment of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA edward.w.yu@case.edu.ORCID 0000-0001-5912-1227
University School · USUniversity of Oklahoma · USNortheastern University · US

Funding

Transport across two membranes by AcrAB-TolC complexR01AI052293 · NIAID · UNIVERSITY OF OKLAHOMA NORMAN · PI ZGURSKAYA, HELEN I · 2003 to 2024
$7.7M
Permeability Barriers of Gram-negative Pathogens and Approaches to Bypass ThemR01AI132836 · NIAID · UNIVERSITY OF OKLAHOMA · PI HELEN I ZGURSKAYA · 2017 to 2026
$4.3M
Emerging antibiotic resistance in Gram-negative pathogensR01AI145069 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI YU, EDWARD W · 2019 to 2023
$3.3M
NIAID NIH HHS R01 AI052293NIAID NIH HHS R01 AI132836NIAID NIH HHS R01 AI145069
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cryoelectron MicroscopyAcinetobacter baumanniiAnti-Bacterial AgentsBacterial ProteinsCell DivisionDrug Resistance, Multiple, BacterialEthidiumMembrane Transport ProteinsAdeB protein, Acinetobacter baumanniiAnti-Bacterial AgentsBacterial ProteinsEthidiumMembrane Transport ProteinsAcinetobacter baumanniiAdeB multidrug efflux pumpcryo-EMmultidrug resistancestructural biology

Identifiers

PMID33622726
PMCPMC8545137
OpenAlexW3130796102

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.