Evidence map›Paper›PMID 33622717›Full record

ArticlemBio2021

Unraveling the Impact of Secreted Proteases on Hypervirulence in

Brittney D Gimza, Jessica K Jackson, Andrew M Frey, Bridget G Budny, Dale Chaput, Devon N Rizzo, Lindsey N Shaw

Open access · goldAbstract read
In one paragraph

Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. The secreted proteasesVirulence · 2025
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  9. Monoclonal antibody neutralizesInfection and immunity · 2025
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  11. Microorganisms · 2025
    Review
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  14. AirwayInfection and immunity · 2025
    Article
  15. The ability ofInfection and immunity · 2025
    Article
  16. Microorganisms · 2025
    Article
  17. Article
  18. Genetic Complexity of CC5Pathogens (Basel, Switzerland) · 2024
    Article
  19. Article
  20. Draft genome sequence of a highly proteolyticMicrobiology resource announcements · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Brittney D GimzaDepartment of Cell Biology, Microbiology, and Molecular Biology, University of South Florida, Tampa, Florida, USA.
Jessica K JacksonDepartment of Cell Biology, Microbiology, and Molecular Biology, University of South Florida, Tampa, Florida, USA.
Andrew M FreyDepartment of Cell Biology, Microbiology, and Molecular Biology, University of South Florida, Tampa, Florida, USA.
Bridget G BudnyDepartment of Cell Biology, Microbiology, and Molecular Biology, University of South Florida, Tampa, Florida, USA.
Dale ChaputDepartment of Cell Biology, Microbiology, and Molecular Biology, University of South Florida, Tampa, Florida, USA.
Devon N RizzoDepartment of Cell Biology, Microbiology, and Molecular Biology, University of South Florida, Tampa, Florida, USA.
Lindsey N ShawDepartment of Cell Biology, Microbiology, and Molecular Biology, University of South Florida, Tampa, Florida, USA shaw@usf.edu.ORCID 0000-0002-0629-8990
University of South Florida · US

Funding

The Role and Regulation of Extracellular Proteases in Staphylococcus aureusR01AI124458 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI SHAW, LINDSEY NEIL · 2017 to 2020
$1.7M
NIAID NIH HHS R01 AI124458
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gene Expression Regulation, BacterialPeptide HydrolasesProteomicsStaphylococcus aureusVirulenceVirulence FactorsPeptide HydrolasesVirulence FactorsproteasesStaphylococcus aureustoxinsvirulence regulation

Identifiers

PMID33622717
PMCPMC8545110
OpenAlexW3132210660

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.