Evidence map›Paper›PMID 33622715›Full record

ArticlemBio2021

Antifungal Liposomes Directed by Dectin-2 Offer a Promising Therapeutic Option for Pulmonary Aspergillosis.

Suresh Ambati, Emma C Ellis, Tuyetnhu Pham, Zachary A Lewis, Xiaorong Lin, Richard B Meagher

Open access · goldAbstract read
In one paragraph

Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Polyphenol-Loaded Liposomal Nanocarriers fromMolecules (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Altering the ligand specificity of DectiSomes.The Journal of biological chemistry · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. The pathobiology of human fungal infections.Nature reviews. Microbiology · 2024
    Review
  9. Article
  10. Article
  11. Fungal Drug Response and Antimicrobial Resistance.Journal of fungi (Basel, Switzerland) · 2023
    Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Suresh AmbatiDepartment of Genetics, University of Georgia, Athens, Georgia, USA.
Emma C EllisDepartment of Genetics, University of Georgia, Athens, Georgia, USA.
Tuyetnhu PhamDepartment of Microbiology, University of Georgia, Athens, Georgia, USA.
Zachary A LewisDepartment of Microbiology, University of Georgia, Athens, Georgia, USA.ORCID 0000-0002-1735-8266
Xiaorong LinDepartment of Microbiology, University of Georgia, Athens, Georgia, USA Xiaorong.Lin@uga.edu meagher@uga.edu.ORCID 0000-0002-3390-8387
Richard B MeagherDepartment of Genetics, University of Georgia, Athens, Georgia, USA Xiaorong.Lin@uga.edu meagher@uga.edu.
University of Georgia · US

Funding

Targeted Pan-Antifungal LiposomesR01AI162989 · NIAID · UNIVERSITY OF GEORGIA · PI Zachary Lewis, Richard Brian Meagher · 2022 to 2026
$2.6M
Antifungal Liposomes Targeted to Cell Wall MannansR21AI148890 · NIAID · UNIVERSITY OF GEORGIA · PI MEAGHER, RICHARD BRIAN · 2020 to 2021
$415k
Antifungal ImunoliposomesR21AI144498 · NIAID · UNIVERSITY OF GEORGIA · PI MEAGHER, RICHARD BRIAN · 2019 to 2020
$415k
NIAID NIH HHS R01 AI162989NIAID NIH HHS R21 AI144498NIAID NIH HHS R21 AI148890
6 · The paper itself

Abstract

Invasive fungal diseases cause millions of deaths each year. There are currently approximately 300,000 acute cases of aspergillosis, most of which result from a pulmonary infection of immunocompromised patients by the common soil organism and opportunistic pathogen

Indexed as

Amphotericin BAnimalsAntifungal AgentsAspergillus fumigatusCell WallFemaleLectins, C-TypeLiposomesMiceNeutropeniaPulmonary AspergillosisAmphotericin BAntifungal Agentsdectin-2, mouseLectins, C-Typeliposomal amphotericin BLiposomesamphotericin Bantifungalsdectinsliposomestargeted drug delivery

Identifiers

PMID33622715
PMCPMC8545082
OpenAlexW3131842896

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.