ArticleThe British journal of ophthalmology2022
Development of the retina and its relation with myopic shift varies from childhood to adolescence.
Article in The British journal of ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 18 citations in OpenAlex.
- Changes in choroidal and retinal thickness 6 months before and during 18 months of orthokeratology lens treatment in myopic children.Acta ophthalmologica · 2026Article
- The IGF2-ERK-Fos axis drives a Müller cell glial-mesenchymal transition-like response to disrupt retinal homeostasis in early myopia.Cell communication and signaling : CCS · 2026Article
- Analysis of the Correlations between Relative Peripheral Refraction Errors and Myopia in Children and Adolescents.Ophthalmology and therapy · 2026Article
- Short-Term Changes in Retinal Activity With Four Myopia Control Spectacle Lenses.Translational vision science & technology · 2026Article
- An Evaluation of the Retinal Nerve Fibre Layer and Ganglion Cell Layer Thickness in Low Myopes.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026Observational
- Comparison of Two Spectral-Domain Optical Coherence Tomographs for Macular Thickness in Romanian Children Reveals Device-Dependent Normative Data and Significant Gender Differences.Diagnostics (Basel, Switzerland) · 2026Article
- A comparison of retinal vascular oxygen saturation between myopic children and adults.BMC ophthalmology · 2026Observational
- Short-Term Choroidal and Retinal Structural Changes in Myopic Children Treated with 0.05% Atropine.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- Repeatability, reproducibility, and agreement for three optical coherence tomography instruments.BMC ophthalmology · 2025Article
- Observations on relative peripheral refraction in Chinese adults with myopia based on a novel application of multispectral refraction topography.Scientific reports · 2024Observational
- Nutritional intake, environmental factors, and their impact on myopia prevalence in Korean children aged 5-12 years.Journal of health, population, and nutrition · 2024Article
- Assessment of macular choroidal and retinal thickness: a cohort study in Tibetan healthy children.Scientific reports · 2024Article
- Study on the Optic Nerve Fiber Layer Thickness and Changes in Blood Flow in Myopic Children.International journal of general medicine · 2021Article
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsTo elucidate the influence of age and myopic shift on retinal development.
methodsThis 1-year longitudinal study included 769 participants aged 6-17 years. Cycloplegic refraction, axial length and swept-source optical coherence tomography were examined at baseline and follow-up. The thickness changes in the retina, ganglion cell complex (GCC) and outer retinal layers (ORL) in the macular region were calculated, and their relation with age and myopic shift was analysed with multiple linear regression analysis.
resultsThe thickness of the central foveal retinal layers was increased in children (<10 years) but unchanged or decreased in adolescents (>13 years). The thickness changes in the retina, GCC and ORL decreased with age (r=-0.24,-0.23, -0.15, respectively, all p<0.01). Multiple regression analysis showed that the changes in central foveal retinal thickness (RT) and GCC thickness were independently associated with age and baseline spherical equivalent (SE), while the changes in ORL thickness were associated with age and SE changes. In children 8-9 years, a greater increase was observed in central foveal ORL thickness in those with no myopic shift (p<0.01). The thickness of the most parafoveal and perifoveal retinal layers was less increased or more decreased in children <9 years with myopic shift (p<0.05).
conclusionsRetinal development and its relation with myopic shift varies from childhood to adolescence. Myopia-related retinal thinning may result from less increase in the RT in childhood rather than a decrease in RT in adolescents. Children under 9 years old could be at a critical age for future myopia-related retinal thinning.
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