Evidence map›Paper›PMID 33622645›Full record

ArticleHematology, transfusion and cell therapy

Improving awareness of several combination therapies for acute myeloid leukemia among oncology and hematology team members in Colorado, USA.

Rovshan M Ismailov, Dyana T Saenz, Pere Gascon, Marcio Nucci, Zaytuna D Khasanova

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Article in Hematology, transfusion and cell therapy. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rovshan M IsmailovComplex Mechanisms of Disease, Aging and Trauma (CMDAT) Research Foundation, Denver, CO, United States. Electronic address: dr.ismailov@cmdat.org.
Dyana T SaenzThe University of Texas M.D. Anderson Cancer Center, Houston TX, United States.
Pere GasconHospital Clínic de Barcelona, University of Barcelona, Barcelona, Spain.
Marcio NucciUniversidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, RJ, Brazil.
Zaytuna D KhasanovaComplex Mechanisms of Disease, Aging and Trauma (CMDAT) Research Foundation, Denver, CO, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAlthough several combination therapies for acute myeloid leukemia (AML) have emerged recently, there has been a lack of published surveys and educational projects focused on these important treatment options. We aimed to improve the oncology team members' knowledge and awareness of several FDA approved combination therapies for AML, including glasdegib (DAURISMO®), venetoclax (VENCLEXTA®), GO (MYOLOTARG®),CPX-351 (VYXEOS®), and midostaurin (RYDAPT®). Additionally, we aimed to examine these teams' perspectives, views, and attitudes towards these topics and finally identify barriers to the implementationof such therapies in clinical practice.

methodInitially, we developed booklets and then distributed them to each participating oncology and hematology office. Subsequently, all participating oncology and hematology team members were asked to complete an anonymous online survey to test their knowledge of and attitudes toward the subjects. MAIN

resultsThere was a total of 52 survey respondents. The correct answer regarding various combination therapies for AML was identified by nearly 70% or more of survey takers. The level of awareness of project subjects significantly improved after reading our printing materials. Many survey respondents were motivated to learn more about combination therapies for AML as well as discuss these topics with others.

conclusionsOur booklets effectively improved understanding and awareness of combination therapies for AML. Future studies should explore awareness, knowledge, and perception of other new and emerging combination therapies for AML among oncology and hematology team members in other areas.

Indexed as

Acute myeloid leukemiaCombination therapiesEducationSurvey

Identifiers

PMID33622645
PMCPMC9477762

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.