Evidence map›Paper›PMID 33622490›Full record

ArticleEmerging infectious diseases2021

Bedaquiline as Treatment for Disseminated Nontuberculous Mycobacteria Infection in 2 Patients Co-Infected with HIV.

Eliza Gil, Nicola Sweeney, Veronica Barrett, Stephen Morris-Jones, Robert F Miller, Victoria J Johnston, Michael Brown

Open access · diamondAbstract read
In one paragraph

Article in Emerging infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Therapy ofMicroorganisms · 2024
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Pharmacologic Management ofOpen forum infectious diseases · 2022
    Review
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Eliza Gil
Nicola Sweeney
Veronica Barrett
Stephen Morris-Jones
Robert F Miller
Victoria J Johnston
Michael Brown
National Health Service · GBLondon School of Hygiene & Tropical Medicine · GBUniversity College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nontuberculous mycobacteria can cause disseminated infections in immunocompromised patients and are challenging to treat because of antimicrobial resistance and adverse effects of prolonged multidrug treatment. We report successful treatment with bedaquiline, a novel antimycobacterial drug, as part of combination therapy for 2 patients with disseminated nontuberculous mycobacteria co-infected with HIV.

Indexed as

CoinfectionHIV InfectionsMycobacterium Infections, NontuberculousDiarylquinolinesHumansNontuberculous MycobacteriabedaquilineDiarylquinolines18fluorodeoxyglucose-positron emission tomography/computed tomography imagingantibacterial drugsantiinfective drugsantimicrobial resistanceantitubercular drugsbacteriabedaquilineco-infectionHIVMycobacteriaceaeMycobacteriumMycobacterium abscessusMycobacterium aviumnontuberculous mycobacteriaNTMrespiratory infectionstuberculosis and other mycobacteriaviruses

Identifiers

PMID33622490
PMCPMC7920675
OpenAlexW3129283003

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.