Evidence map›Paper›PMID 33622466›Full record

ReviewEmerging infectious diseases2021

Decentralized Care for Rifampin-Resistant Tuberculosis, Western Cape, South Africa.

Sarah V Leavitt, Karen R Jacobson, Elizabeth J Ragan, Jacob Bor, Jennifer Hughes, Tara C Bouton, Tania Dolby, Robin M Warren, Helen E Jenkins

Abstract readReview
In one paragraph

Review in Emerging infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Experiences of key populations in multidrug-resistant TB and HIV.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sarah V Leavitt
Karen R Jacobson
Elizabeth J Ragan
Jacob Bor
Jennifer Hughes
Tara C Bouton
Tania Dolby
Robin M Warren
Helen E Jenkins

Funding

Translational ScienceP30AI042853 · NIAID · MIRIAM HOSPITAL · PI CURT G BECKWITH, DEBBIE M. CHENG · 1998 to 2026
$51.7M
HIV and Other Infectious Consequences of Substance UseT32DA013911 · NIDA · MIRIAM HOSPITAL · PI TRACI C GREEN, JOSIAH D RICH · 2001 to 2026
$9.6M
Transmission Of Tuberculosis Among illicit drug use Linkages (TOTAL)R01AI147316 · NIAID · BOSTON MEDICAL CENTER · PI JACOBSON, KAREN R · 2019 to 2023
$3.5M
The impact of alcohol consumption on TB treatment outcomesR01AI119037 · NIAID · BOSTON MEDICAL CENTER · PI JACOBSON, KAREN R · 2016 to 2020
$3.3M
Interdisciplinary Training for BiostatisticiansT32GM074905 · NIGMS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI WHITE, LAURA FORSBERG · 2005 to 2019
$3.0M
Evaluating the tuberculosis epidemic in South Africa using a novel ten-year cohortR01AI152126 · NIAID · WITS HEALTH CONSORTIUM (PTY), LTD · PI JENKINS, HELEN E., SCOTT, LESLEY · 2020 to 2024
$1.6M
Geospatial clustering and molecular and social epidemiology of drug resistant TBK01TW009213 · FIC · MASSACHUSETTS GENERAL HOSPITAL · PI JACOBSON, KAREN R · 2011 to 2015
$715k
Understanding spatial heterogeneity of drug resistant tuberculosisK01AI102944 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI JENKINS, HELEN E. · 2013 to 2017
$627k
Tracking drug-resistant tuberculosis patients through time in South AfricaR03AI144335 · NIAID · BOSTON UNIVERSITY MEDICAL CAMPUS · PI JENKINS, HELEN E. · 2019 to 2020
$165k
FIC NIH HHS K01 TW009213NIAID NIH HHS K01 AI102944NIAID NIH HHS P30 AI042853NIAID NIH HHS R01 AI119037NIAID NIH HHS R01 AI147316NIAID NIH HHS R01 AI152126NIAID NIH HHS R03 AI144335NIDA NIH HHS T32 DA013911NIGMS NIH HHS T32 GM074905
6 · The paper itself

Abstract

In 2011, South Africa implemented a policy to decentralize treatment for rifampin-resistant tuberculosis (TB) to reduce durations of hospitalization and enable local treatment. We assessed policy implementation in Western Cape Province, where services expanded from 6 specialized TB hospitals to 406 facilities, by analyzing National Health Laboratory Service data on TB during 2012-2015. We calculated the percentage of patients who visited a TB hospital <1 year after rifampin-resistant TB diagnosis, the median duration of their hospitalizations, and the total distance between facilities visited. We assessed temporal changes with linear regression and stratified results by location. Of 2,878 patients, 65% were from Cape Town. In Cape Town, 29% visited a TB hospital; elsewhere, 68% visited a TB hospital. We found that hospitalizations and travel distances were shorter in Cape Town than in the surrounding areas.

Indexed as

TuberculosisTuberculosis, Multidrug-ResistantHumansRifampinSouth AfricaRifampinantimicrobial resistancebacteriadecentralized caredrug resistancehealth policyhospitalizationrespiratory infectionsrifampinrifampin-resistantroutinely collected dataSouth Africatreatmenttuberculosis

Identifiers

PMID33622466
PMCPMC7920662

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.