Evidence map›Paper›PMID 33622377›Full record

ReviewNutrition & metabolism2021

A comprehensive review of long non-coding RNAs in the pathogenesis and development of non-alcoholic fatty liver disease.

Arezoo Gowhari Shabgah, Fatemeh Norouzi, Mahdiyeh Hedayati-Moghadam, Davood Soleimani, Naseh Pahlavani, Jamshid Gholizadeh Navashenaq

Open access · goldAbstract readReview
In one paragraph

Review in Nutrition & metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Pooled it
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  7. Review
  8. Article
  9. LncRNAInternational journal of molecular sciences · 2024
    Article
  10. Long Noncoding RNAs in Diet-Induced Metabolic Diseases.International journal of molecular sciences · 2024
    Review
  11. Review
  12. Article
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  14. Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Arezoo Gowhari ShabgahSchool of Medicine, Bam University of Medical Sciences, Bam, Iran.
Fatemeh NorouziDepartment of Food Hygiene, Faculty of Veterinary Medicine, Shahid Chamran University of Ahvaz, Ahvaz, Iran.
Mahdiyeh Hedayati-MoghadamDepartment of Physiology, School of Medicine, Jiroft University of Medical Sciences, Jiroft, Iran.
Davood SoleimaniDepartment of Nutritional Sciences, School of Nutrition Sciences and Food Technology, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Naseh PahlavaniSocial Development and Health Promotion Research Center, Gonabad University of Medical Sciences, Gonabad, Iran.
Jamshid Gholizadeh NavashenaqNoncommunicable Diseases Research Center, Bam University of Medical Sciences, Bam, Iran. jamshid.gholizadeh@gmail.com.ORCID http://orcid.org/0000-0002-3073-5302
Bam University of Medical Sciences · IRGonabad University of Medical Sciences · IRKermanshah University of Medical Sciences · IRShahid Chamran University of Ahvaz · IRUniversity of Jiroft · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One of the most prevalent diseases worldwide without a fully-known mechanism is non-alcoholic fatty liver disease (NAFLD). Recently, long non-coding RNAs (lncRNAs) have emerged as significant regulatory molecules. These RNAs have been claimed by bioinformatic research that is involved in biologic processes, including cell cycle, transcription factor regulation, fatty acids metabolism, and-so-forth. There is a body of evidence that lncRNAs have a pivotal role in triglyceride, cholesterol, and lipoprotein metabolism. Moreover, lncRNAs by up- or down-regulation of the downstream molecules in fatty acid metabolism may determine the fatty acid deposition in the liver. Therefore, lncRNAs have attracted considerable interest in NAFLD pathology and research. In this review, we provide all of the lncRNAs and their possible mechanisms which have been introduced up to now. It is hoped that this study would provide deep insight into the role of lncRNAs in NAFLD to recognize the better molecular targets for therapy.

Indexed as

Fatty liverLncRNANAFLDNASHNon-coding RNA

Identifiers

PMID33622377
PMCPMC7903707
OpenAlexW3130655994

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.