Evidence map›Paper›PMID 33622353›Full record

ArticleEnvironmental health : a global access science source2021

Assessing additive effects of air pollutants on mortality rate in Massachusetts.

Yaguang Wei, Brent Coull, Petros Koutrakis, Jiabei Yang, Longxiang Li, Antonella Zanobetti, Joel Schwartz

Abstract read
In one paragraph

Article in Environmental health : a global access science source, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Additive effects of 10-year exposures to PMEnvironmental epidemiology (Philadelphia, Pa.) · 2023
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yaguang WeiDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Landmark Center 4th West, 401 Park Drive, Boston, MA, 02215, USA. weiyg@g.harvard.edu.ORCID 0000-0002-6796-7510
Brent CoullDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Petros KoutrakisDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Landmark Center 4th West, 401 Park Drive, Boston, MA, 02215, USA.
Jiabei YangDepartment of Biostatistics, School of Public Health, Brown University, Providence, RI, USA.
Longxiang LiDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Landmark Center 4th West, 401 Park Drive, Boston, MA, 02215, USA.
Antonella ZanobettiDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Landmark Center 4th West, 401 Park Drive, Boston, MA, 02215, USA.
Joel SchwartzDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Landmark Center 4th West, 401 Park Drive, Boston, MA, 02215, USA.

Funding

Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI JAIME ELIZABETH HART · 1985 to 2026
$44.6M
Project 3: Cumulative Risk and Geospatial Health Disparities Related to Chemical and Non-Chemical Stressor ExposuresP50MD010428 · NIMHD · HARVARD SCHOOL OF PUBLIC HEALTH · PI LADEN, FRANCINE, LEVY, JONATHAN I · 2015 to 2020
$4.0M
Cardiovascular Health and Air Pollution: A National StudyR01ES024332 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI ZANOBETTI, ANTONELLA · 2015 to 2018
$2.5M
NIEHS NIH HHS P30 ES000002NIEHS NIH HHS R01 ES024332NIMHD NIH HHS P50 MD010428
6 · The paper itself

Abstract

backgroundWe previously found additive effects of long- and short-term exposures to fine particulate matter (PM

methodsWe proposed two new methods and reconducted the analysis using the same cohort of Medicare beneficiaries in Massachusetts during 2000-2012, which consisted of 1.5 million individuals with 3.8 billion person-days of follow-up. The first method, weighted least squares (WLS), leveraged large volume of data by aggregating person-days, which gave equivalent results to the linear probability model (LPM) method in the previous analysis but significantly reduced computational burden. The second method, m-out-of-n random forests (moonRF), implemented scaling random forests that captured all possible interactions and nonlinearities in the GPS model. To minimize confounding bias, we additionally controlled relative humidity and health care utilizations that were not included previously. Further, we performed low-level analysis by restricting to person-days with exposure levels below increasingly stringent thresholds.

resultsWe found consistent results between LPM/WLS and moonRF: all exposures were positively associated with mortality rate, even at low levels. For long-term PM

conclusionsThis study provides more rigorous causal evidence between PM

Indexed as

MortalityAgedAged, 80 and overAir PollutantsEnvironmental ExposureFemaleHumansLeast-Squares AnalysisLinear ModelsMaleMassachusettsMedicareNitrogen DioxideOzoneParticulate MatterPropensity ScoreAir PollutantsNitrogen DioxideOzoneParticulate MatterAir pollutionCausalityData aggregationGeneralized propensity scoreScaling random forests

Identifiers

PMID33622353
PMCPMC7903765

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.