SynthesisRadiation oncology (London, England)2021
Can internal mammary lymph nodes irradiation bring survival benefits for breast cancer patients? A systematic review and meta-analysis of 12,705 patients in 12 studies.
Synthesis in Radiation oncology (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Clinical outcomes of postoperative radiotherapy with regional nodal irradiation excluding internal mammary lymph nodes in breast cancer: a multi-institutional retrospective analysis.Breast cancer (Tokyo, Japan) · 2026Article
- Impact of excluding internal mammary node coverage on musculoskeletal dosimetry in breast radiotherapy.Clinical and translational radiation oncology · 2026Article
- Cardiac substructure dosimetry in postoperative breast-conserving radiotherapy: a novel 8-field IMRT approach for internal mammary node irradiation using MONACO.Frontiers in oncology · 2025Article
- Oncoplastic Breast Conservation for Central Tumors: Definition, Classification, and the Analysis of Single Institution Experience.Plastic and reconstructive surgery. Global open · 2024Article
- A Questionnaire Survey of Current Practice in the Management of Internal Mammary Lymph Nodes in Breast Cancer.South Asian journal of cancer · 2024Article
- Interstitial brachytherapy for internal mammary node in breast cancer: A case report.Journal of contemporary brachytherapy · 2023Article
- A dose planning study for cardiac and lung dose sparing techniques in left breast cancer radiotherapy: Can free breathing helical tomotherapy be considered as an alternative for deep inspiration breath hold?Technical innovations & patient support in radiation oncology · 2023Article
- The optimal regional irradiation volume for breast cancer patients: A comprehensive systematic review and network meta-analysis of published studies.Frontiers in oncology · 2023Article
- Internal mammary lymph nodal response to neoadjuvant chemotherapy on imaging and breast cancer prognosis.Annals of medicine and surgery (2012) · 2022Article
- Breast Cancer MCF-7 Cell Spheroid Culture for Drug Discovery and Development.Journal of cancer therapy · 2022Article
- Evaluation of the Property of Axillary Lymph Nodes and Analysis of Lymph Node Metastasis Factors in Breast Cancer by Ultrasound Elastography.Computational and mathematical methods in medicine · 2022Article
- Surface guided 3DCRT in deep-inspiration breath-hold for left sided breast cancer radiotherapy: implementation and first clinical experience in Iran.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2022Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the effect of prophylactic irradiation of internal mammary lymph nodes in breast cancer patients.
methodsThe computer searched PubMed, EMBASE, Web of science, CNKI, Wanfang Medical Network, the Chinese Biomedical Literature Database to find clinical studies on internal mammary lymph node irradiation (IMNI) in breast cancer. The quality of the included literature was evaluated according to the Newcastle-Ottawa scale. Stata14 software was used for meta-analysis.
resultsA total of 12,705 patients in 12 articles were included for meta-analyzed. Compared with patients who unirradiated internal mammary lymph nodes (non-IMNI), the risk of death for patients after IMNI was reduced by 11% (HR 0.89, 95% CI 0.79-1.00, P = 0.0470); DFS of group mixed N
conclusionUnder modern radiotherapy techniques, IMNI can safely and effectively bring clinical benefits to N
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