Evidence map›Paper›PMID 33622263›Full record

ArticleBMC infectious diseases2021

Description of two fatal cases of melioidosis in Mexican children with acute pneumonia: case report.

Gerardo Alvarez-Hernandez, Denica Cruz-Loustaunau, J Antonio Ibarra, Adela Rascon-Alcantar, Jesús Contreras-Soto, Georgina Meza-Radilla, Alfredo G Torres, Paulina Estrada-de Los Santos

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Gerardo Alvarez-HernandezDepartment of Medicine and Health Sciences, University of Sonora, Hermosillo, Sonora, Mexico.
Denica Cruz-LoustaunauMinistry of Health of Sonora, Hermosillo, Sonora, Mexico.
J Antonio IbarraInstituto Politécnico Nacional, Escuela Nacional de Ciencias Biológicas, Prol. Carpio y Plan de Ayala s/n, Col. Santo Tomás, Alcaldía Miguel Hidalgo. C.P., 11340, Mexico City, Mexico.
Adela Rascon-AlcantarSonora Children's Hospital, Hermosillo, Sonora, Mexico.
Jesús Contreras-SotoSonora Children's Hospital, Hermosillo, Sonora, Mexico.
Georgina Meza-RadillaInstituto Politécnico Nacional, Escuela Nacional de Ciencias Biológicas, Prol. Carpio y Plan de Ayala s/n, Col. Santo Tomás, Alcaldía Miguel Hidalgo. C.P., 11340, Mexico City, Mexico.
Alfredo G TorresUniversity of Texas Medical Branch, Galveston, TX, USA.
Paulina Estrada-de Los SantosInstituto Politécnico Nacional, Escuela Nacional de Ciencias Biológicas, Prol. Carpio y Plan de Ayala s/n, Col. Santo Tomás, Alcaldía Miguel Hidalgo. C.P., 11340, Mexico City, Mexico. pestradadelossantos@gmail.com.ORCID http://orcid.org/0000-0003-2407-0284
Instituto Politécnico Nacional · MXUniversidad de Sonora · MXThe University of Texas Medical Branch at Galveston · US

Funding

Secretaría de Investigación y Posgrado, Instituto Politécnico Nacional SIP20196674
6 · The paper itself

Abstract

backgroundMelioidosis is an infectious disease caused by Burkholderia pseudomallei. In Mexico, the disease is rarely diagnosed in humans and there is no evidence of simultaneous environmental isolation of the pathogen. Here, we describe clinical profiles of fatal cases of melioidosis in two children, in a region without history of that disease. CASE PRESENTATION: About 48 h before onset of symptoms, patients swam in a natural body of water, and thereafter they rapidly developed fatal septicemic illness. Upon necropsy, samples from liver, spleen, lung, cerebrospinal fluid, and bronchial aspirate tissues contained Burkholderia pseudomallei. Environmental samples collected from the locations where the children swam also contained B. pseudomallei. All the clinical and environmental strains showed the same BOX-PCR pattern, suggesting that infection originated from the area where the patients were swimming.

conclusionsThe identification of B. pseudomallei confirmed that melioidosis disease exists in Sonora, Mexico. The presence of B. pseudomallei in the environment may suggest endemicity of the pathogen in the region. This study highlights the importance of strengthening laboratory capacity to prevent and control future melioidosis cases.

Indexed as

AdolescentBurkholderia pseudomalleiChildFatal OutcomeFemaleHumansMaleMelioidosisMexicoPneumonia, BacterialSepsisSwimmingBurkholderia pseudomalleiCase reportFatal outcomeMelioidosis

Identifiers

PMID33622263
PMCPMC7903701
OpenAlexW3133229048

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.