ArticleBMC gastroenterology2021
Functional outcomes of patients with short-segment Hirschsprung disease after transanal endorectal pull-through.
Article in BMC gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Perioperative outcomes in primary neonatal pullthrough versus pullthrough in older children with Hirschsprung disease: a systematic review and meta-analysis.Scientific reports · 2026Pooled it
- Evaluation of Trans-Anal Endorectal Pull-Through Outcomes in Hirschsprung's Disease in Different Age Groups: A Comprehensive Systematic Review.Archives of Iranian medicine · 2024Pooled it
- Perioperative and Long-Term Functional Outcomes of Children With Early Diagnosis Versus Late Diagnosis of Hirschsprung's Disease: A 30-Year Monocentric Retrospective Study.International journal of pediatrics · 2026Article
- Review
- The association between short-term postoperative complications and bowel function after surgery for Hirschsprung disease.BMC pediatrics · 2025Article
- Early Outcomes of Hirschsprung's Disease after Definitive Surgery: A Ten-year Experience.Current pediatric reviews · 2025Article
- Minimally Invasive Surgery for Hirschsprung Disease: Current Practices and Future Directions.Cureus · 2024Review
- Peri-anal infiltration versus caudal block for multimodal analgesia in paediatric patients with Hirschsprung's disease undergoing transanal endorectal pull-through procedure: A randomised trial.Indian journal of anaesthesia · 2023Article
- Long-term bowel function after single-stage transanal endorectal pull-through in neonatal patients with Hirschsprung disease.Pediatric surgery international · 2023Article
- Prognostic factors for persistent obstructive symptoms in patients with Hirschsprung disease following pull-through.PloS one · 2023Article
- One-stage transanal endorectal pull-through for Hirschsprung disease: experience with 229 neonates.Pediatric surgery international · 2022Article
- Long-term functional outcomes of patients with Hirschsprung disease following pull-through.BMC pediatrics · 2022Article
- Comparison of Two Different Cut-Off Values of Scoring System for Diagnosis of Hirschsprung-Associated Enterocolitis After Transanal Endorectal Pull-Through.Frontiers in pediatrics · 2021Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTransanal endorectal pull-through (TEPT) is considered the most preferable treatment method for Hirschsprung disease (HSCR) since it is less invasive and has fewer morbidities than transabdominal pull-through. Here, functional outcomes in short-segment HSCR patients after TEPT were assessed and associated with the prognostic factors.
methodsKrickenbeck classification was used to assess the functional outcomes in patients with HSCR after TEPT surgery at our institution from 2012 to 2020.
resultsFifty patients were involved in this study. Voluntary bowel movement (VBM) was achieved in 82% of subjects. Nine (18%) subjects had soiling grade 1, while two (4%) and two (4%) patients suffered constipation that was manageable with diet and laxative agents, respectively. Patients who underwent TEPT at ≥ 4 years old tended to have soiling more than patients who underwent TEPT at < 4 years old (OR = 16.47 [95% CI 0.9-301.61]; p = 0.06), whereas patients with post-operative complications had 10.5-fold higher risk for constipation than patients without post-operative complications (p = 0.037; 95% CI 1.15-95.92). Multivariate analysis showed male sex was significantly associated with VBM (OR = 9.25 [95% CI 1.34-63.77]; p = 0.024), while post-operative complications were strongly correlated with constipation (OR = 10 [95% CI 1.09-91.44]; p = 0.04).
conclusionsThe functional outcomes of HSCR patients after TEPT in our institution are considered relatively good. Moreover, the VBM, soiling, and constipation risk after TEPT might be affected by sex, age at TEPT performed, and post-operative complications, respectively, while the age at TEPT performed might not be associated with functional outcomes. Further multicenter studies with a larger sample size are necessary to clarify and confirm our findings.
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